Fig. 2

The putative effects of PEDF on atherosclerosis progression. From a physiological view, PEDF can alleviate the development of atherosclerosis based on its anti-inflammatory, anti-oxidant, anti-angiogenic and anti-thrombogenic properties. The underlying mechanisms of PEDF are listed that form a concerted set of activities to protect health against atherosclerosis. PEDF, pigment epithelium-derived factor