|
ACE2 SNPs
|
Normotensive
|
Hypertensive
|
OR(95%CI)a
|
P-valuea
|
|---|
|
(N/%)
|
(N/%)
|
|---|
|
rs2074192
|
CC
|
118 (50.6)
|
162(40.3)
|
1.00
| |
| |
TT + CT
|
115 (59.4)
|
240(59.7)
|
1.72 (1.17–2.53)
|
0.006
|
|
rs2106809
|
CC + CT
|
121 (51.9)
|
175(43.5)
|
1.00
| |
| |
TT
|
112(48.1)
|
227(56.5)
|
1.71 (1.13–2.58)
|
0.012
|
|
rs4240157
|
CC + CT
|
43 (18.5)
|
92 (22.9)
|
1.99 (1.17–3.41)
|
0.012
|
| |
TT
|
190 (81.5)
|
310 (77.1)
|
1.00
| |
|
rs4646155
|
CC
|
211 (90.6)
|
334 (83.1)
|
1.00
| |
| |
TT + CT
|
22 (9.4)
|
68 (16.9)
|
1.94 (1.06–3.54)
|
0.030
|
|
rs4646188
|
CC
|
74 (31.8)
|
85 (21.1)
|
1.00
| |
| |
TT + CT
|
159 (68.2)
|
317 (78.9)
|
3.25 (1.95–5.41)
|
< 0.001
|
|
rs4830542
|
CC + CT
|
43 (18.5)
|
90 (22.4)
|
1.88 (1.10–3.23)
|
0.020
|
| |
TT
|
190 (81.5)
|
312 (77.6)
|
1.00
| |
|
rs879922
|
CC + CG
|
40 (17.2)
|
131 (32.6)
|
4.86 (2.74–8.64)
|
< 0.001
|
| |
GG
|
193 (82.8)
|
271 (67.4)
|
1.00
| |
- aAfter adjustment for nationality, gender, age, smoking, BMI, TRIG, LDL-C, HDL-C, Lp(a), FBS, UA, HsCRP and Ang II
