Association of ACE2 polymorphisms with susceptibility to essential hypertension and dyslipidemia in Xinjiang, China

Table 1 Association of ACE2 SNPs with EH in participants

ACE2 SNPs		Normotensive	Hypertensive	OR(95%CI)^a	P-value^a
ACE2 SNPs		(N/%)	(N/%)	OR(95%CI)^a	P-value^a
rs2074192	CC	118 (50.6)	162(40.3)	1.00
	TT + CT	115 (59.4)	240(59.7)	1.72 (1.17–2.53)	0.006
rs2106809	CC + CT	121 (51.9)	175(43.5)	1.00
	TT	112(48.1)	227(56.5)	1.71 (1.13–2.58)	0.012
rs4240157	CC + CT	43 (18.5)	92 (22.9)	1.99 (1.17–3.41)	0.012
	TT	190 (81.5)	310 (77.1)	1.00
rs4646155	CC	211 (90.6)	334 (83.1)	1.00
	TT + CT	22 (9.4)	68 (16.9)	1.94 (1.06–3.54)	0.030
rs4646188	CC	74 (31.8)	85 (21.1)	1.00
	TT + CT	159 (68.2)	317 (78.9)	3.25 (1.95–5.41)	< 0.001
rs4830542	CC + CT	43 (18.5)	90 (22.4)	1.88 (1.10–3.23)	0.020
	TT	190 (81.5)	312 (77.6)	1.00
rs879922	CC + CG	40 (17.2)	131 (32.6)	4.86 (2.74–8.64)	< 0.001
	GG	193 (82.8)	271 (67.4)	1.00

^aAfter adjustment for nationality, gender, age, smoking, BMI, TRIG, LDL-C, HDL-C, Lp(a), FBS, UA, HsCRP and Ang II

ISSN: 1476-511X