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Table 1 Comparison between HBL and non-HBL groups, according to demography and main biological features (n=837)

From: Prevalence of hypobetalipoproteinemia and related psychiatric characteristics in a psychiatric population: results from the retrospective HYPOPSY Study

  HBL
(n=20)
Non-HBL
(n=817)
p - value$
Demography
 Age (± SD); years 35± 10 44± 14 0.0032
 Gender (% Male) 65% 59% 0.36
 Weight (± SD). kg 66 ± 11 72 ± 18 0.094
 BMI (± SD). kg/m2 22 ± 4 25 ± 14 0.0115
Biological features (mg/dL)
 TC (± SD) 123 ± 28 186 ± 40 <0.0001
 LDL-C (± SD) 42 ± 7 109 ± 34 <0.0001
 HDL-C (± SD) 66 ± 30 53 ± 20 0.067
 TG (± SD) 74 ± 52 115 ± 56 <0.0001
Psychotropic drugs
 Psychotropic drug consumption 45% 60% 0.17
 Psychotropic drug with lipid metabolism impacta 25% 39% 0.25
  1. $p-values obtained by Mann-Withney or Fisher exact tests; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol, TC Total cholesterol, TG triglycerides
  2. athese drugs include clozapine, olanzapine, risperidone, aripiprazole, zuclopenthixol, quetiapine, paliperidone, chlopromazine
  3. p-value < 0.05