Prevalence of hypobetalipoproteinemia and related psychiatric characteristics in a psychiatric population: results from the retrospective HYPOPSY Study

Table 1 Comparison between HBL and non-HBL groups, according to demography and main biological features (n=837)

	HBL (n=20)	Non-HBL (n=817)	p - value^$
Demography
Age (± SD); years	35± 10	44± 14	0.0032^¶
Gender (% Male)	65%	59%	0.36
Weight (± SD). kg	66 ± 11	72 ± 18	0.094
BMI (± SD). kg/m²	22 ± 4	25 ± 14	0.0115^¶
Biological features (mg/dL)
TC (± SD)	123 ± 28	186 ± 40	<0.0001^¶
LDL-C (± SD)	42 ± 7	109 ± 34	<0.0001^¶
HDL-C (± SD)	66 ± 30	53 ± 20	0.067
TG (± SD)	74 ± 52	115 ± 56	<0.0001^¶
Psychotropic drugs
Psychotropic drug consumption	45%	60%	0.17
Psychotropic drug with lipid metabolism impact^a	25%	39%	0.25

^$p-values obtained by Mann-Withney or Fisher exact tests; HDL-C high-density lipoprotein cholesterol; LDL-C low-density lipoprotein cholesterol, TC Total cholesterol, TG triglycerides
^athese drugs include clozapine, olanzapine, risperidone, aripiprazole, zuclopenthixol, quetiapine, paliperidone, chlopromazine
^¶p-value < 0.05

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