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Table 1 Antidiabetic effects of DKE

From: Hypolipidemic activity of Dracocephalum kotschyi involves FOXO1 mediated modulation of PPARγ expression in adipocytes

Groups days Glucose (mg/dl) TG (mg/dl) TC (mg/dl) LDL (mg/dl) HDL (mg/dl)
Normal control 0 131.25 ± 3.85* 61.73 ± 2.05* 66.45 ± 5.85* 18.01 ± 1.23* 34.02 ± 0.86*
14 132.00 ± 2.20* 63.98 ± 3.52* 66.81 ± 3.44* 19.55 ± 1.78* 32.68 ± 1.44*
28 127.00 ± 5.30* 62.33 ± 3.87* 67.88 ± 5.31* 20.41 ± 1.26* 35.04 ± 1.46*
Diabetic control 0 290.80 ± 18.20 120.44 ± 4.58 107.76 ± 5.67 56.72 ± 4.05 23.38 ± 0.77
14 342.36 ± 3.96 127.36 ± 4.69 116.54 ± 6.04 65.22 ± 4.11 22.46 ± 1.61
28 393.87 ± 7.97 143.36 ± 8.07 117.09 ± 1.46 76.90 ± 4.24 21.18 ± 1.82
DKE (0.25 ml/rat) 0 412.58 ± 17.82 110.35 ± 8.69 101.72 ± 6.22 66.11 ± 3.56 20.16 ± 1.30
14 384.43 ± 11.07 93.33 ± 4.99* 99.53 ± 5.85 52.80 ± 1.56 23.57 ± 0.57
28 321.07 ± 4.00* 74.15 ± 3.33* 80.74 ± 2.19* 43.75 ± 2.50* 24.34 ± 1.72
DKE (0.5 ml/rat) 0 379.43 ± 8.08 117.16 ± 8.22 106.77 ± 3.59 57.39 ± 1.85 22.16 ± 0.69
14 365.22 ± 3.825 77.62 ± 3.08* 97.88 ± 2.37 44.17 ± 2.06* 26.64 ± 0.77
28 284.80 ± 6.40* 66.33 ± 1.76* 69.89 ± 4.17* 35.26 ± 3.99* 30.74 ± 1.15*
Pioglitazone 0 342.73 ± 21.44 99.78 ± 4.70 116.91 ± 2.44 61.99 ± 3.57 23.23 ± 0.69
14 255.89 ± 7.73* 72.66 ± 3.40* 92.14 ± 1.97* 41.26 ± 1.00* 29.13 ± 0.92
28 178.67 ± 10.01* 63.63 ± 2.82* 72.38 ± 4.46* 24.51 ± 2.04* 33.25 ± 1.05*
  1. Each value represents the mean ± SD (n = 6). *P < 0.05 statistically different compared to the diabetic control by Student’s t-test