Groups
|
days
|
Glucose (mg/dl)
|
TG (mg/dl)
|
TC (mg/dl)
|
LDL (mg/dl)
|
HDL (mg/dl)
|
---|
Normal control
|
0
|
131.25 ± 3.85*
|
61.73 ± 2.05*
|
66.45 ± 5.85*
|
18.01 ± 1.23*
|
34.02 ± 0.86*
|
14
|
132.00 ± 2.20*
|
63.98 ± 3.52*
|
66.81 ± 3.44*
|
19.55 ± 1.78*
|
32.68 ± 1.44*
|
28
|
127.00 ± 5.30*
|
62.33 ± 3.87*
|
67.88 ± 5.31*
|
20.41 ± 1.26*
|
35.04 ± 1.46*
|
Diabetic control
|
0
|
290.80 ± 18.20
|
120.44 ± 4.58
|
107.76 ± 5.67
|
56.72 ± 4.05
|
23.38 ± 0.77
|
14
|
342.36 ± 3.96
|
127.36 ± 4.69
|
116.54 ± 6.04
|
65.22 ± 4.11
|
22.46 ± 1.61
|
28
|
393.87 ± 7.97
|
143.36 ± 8.07
|
117.09 ± 1.46
|
76.90 ± 4.24
|
21.18 ± 1.82
|
DKE (0.25 ml/rat)
|
0
|
412.58 ± 17.82
|
110.35 ± 8.69
|
101.72 ± 6.22
|
66.11 ± 3.56
|
20.16 ± 1.30
|
14
|
384.43 ± 11.07
|
93.33 ± 4.99*
|
99.53 ± 5.85
|
52.80 ± 1.56
|
23.57 ± 0.57
|
28
|
321.07 ± 4.00*
|
74.15 ± 3.33*
|
80.74 ± 2.19*
|
43.75 ± 2.50*
|
24.34 ± 1.72
|
DKE (0.5 ml/rat)
|
0
|
379.43 ± 8.08
|
117.16 ± 8.22
|
106.77 ± 3.59
|
57.39 ± 1.85
|
22.16 ± 0.69
|
14
|
365.22 ± 3.825
|
77.62 ± 3.08*
|
97.88 ± 2.37
|
44.17 ± 2.06*
|
26.64 ± 0.77
|
28
|
284.80 ± 6.40*
|
66.33 ± 1.76*
|
69.89 ± 4.17*
|
35.26 ± 3.99*
|
30.74 ± 1.15*
|
Pioglitazone
|
0
|
342.73 ± 21.44
|
99.78 ± 4.70
|
116.91 ± 2.44
|
61.99 ± 3.57
|
23.23 ± 0.69
|
14
|
255.89 ± 7.73*
|
72.66 ± 3.40*
|
92.14 ± 1.97*
|
41.26 ± 1.00*
|
29.13 ± 0.92
|
28
|
178.67 ± 10.01*
|
63.63 ± 2.82*
|
72.38 ± 4.46*
|
24.51 ± 2.04*
|
33.25 ± 1.05*
|
- Each value represents the mean ± SD (n = 6). *P < 0.05 statistically different compared to the diabetic control by Student’s t-test