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Table 2 The content of major neurotransmitters and their metabolites in the prefrontal cortex

From: Ω-3 fatty acids-supplementary in gestation alleviates neuroinflammation and modulates neurochemistry in rats

Compound

Virgin

Parous

Control

Supplementary

Control

Supplementary

DA (ng/g)

5.3 ± 0.6

5.4 ± 1.2

2.2 ± 0.3##

3.4 ± 0.3#

DOPAC (ng/g)

6.8 ± 0.9

10.1 ± 1.9

10.1 ± 1.0

7.7 ± 0.5

HVA (ng/g)

1.1 ± 0.2

1.3 ± 0.3

1.3 ± 0.1

1.8 ± 0.2

NE (ng/g)

8.2 ± 1.8

3.8 ± 0.9**

3.3 ± 0.6##

5.9 ± 0.7

MHPG (ng/g)

0.7 ± 0.1

0.9 ± 0.1

0.9 ± 0.1

1.1 ± 0.1

VMA(ng/g)

1.2 ± 0.1

2.0 ± 0.4*

0.6 ± 0.1

0.5 ± 0.1##

TRY (ug/g)

9.2 ± 1.6

6.7 ± 1.4

8.2 ± 0.7

12.0 ± 1.0##,*

5-HT (ng/g)

153.7 ± 14.0

127.7 ± 31.3

116.0 ± 14.6

178.6 ± 26.1

5-HIAA (ng/g)

373.9 ± 45.6

355.6 ± 27.0

304.0 ± 25.8

215.3 ± 11.02##,*

5-HIAA/5-HT

3.0 ± 0.4

3.2 ± 0.8

2.8 ± 0.4

1.2 ± 0.2#,*

KYN (ng/g)

540.7 ± 99.0

429.0 ± 101.2

526.1 ± 51.4

622.2 ± 58.8

GABA (ug/g)

292.6 ± 41.5

200.3 ± 49.8

602.7 ± 82.8##

730.1 ± 99.2##

GLU (ug/g)

0.4 ± 0.06

0.3 ± 0.05

0.5 ± 0.06

0.7 ± 0.07

GLN (ug/g)

178.2 ± 25.2

132.0 ± 35.8

356.7 ± 41.5#

501.0 ± 64.2##

  1. Data are means ± SEM (n = 6–7). #p < 0.05, ##p < 0.01 compared to virgin group; *p < 0.05, **p < 0.01compared to control group