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Table 2 The content of major neurotransmitters and their metabolites in the prefrontal cortex

From: Ω-3 fatty acids-supplementary in gestation alleviates neuroinflammation and modulates neurochemistry in rats

Compound Virgin Parous
Control Supplementary Control Supplementary
DA (ng/g) 5.3 ± 0.6 5.4 ± 1.2 2.2 ± 0.3## 3.4 ± 0.3#
DOPAC (ng/g) 6.8 ± 0.9 10.1 ± 1.9 10.1 ± 1.0 7.7 ± 0.5
HVA (ng/g) 1.1 ± 0.2 1.3 ± 0.3 1.3 ± 0.1 1.8 ± 0.2
NE (ng/g) 8.2 ± 1.8 3.8 ± 0.9** 3.3 ± 0.6## 5.9 ± 0.7
MHPG (ng/g) 0.7 ± 0.1 0.9 ± 0.1 0.9 ± 0.1 1.1 ± 0.1
VMA(ng/g) 1.2 ± 0.1 2.0 ± 0.4* 0.6 ± 0.1 0.5 ± 0.1##
TRY (ug/g) 9.2 ± 1.6 6.7 ± 1.4 8.2 ± 0.7 12.0 ± 1.0##,*
5-HT (ng/g) 153.7 ± 14.0 127.7 ± 31.3 116.0 ± 14.6 178.6 ± 26.1
5-HIAA (ng/g) 373.9 ± 45.6 355.6 ± 27.0 304.0 ± 25.8 215.3 ± 11.02##,*
5-HIAA/5-HT 3.0 ± 0.4 3.2 ± 0.8 2.8 ± 0.4 1.2 ± 0.2#,*
KYN (ng/g) 540.7 ± 99.0 429.0 ± 101.2 526.1 ± 51.4 622.2 ± 58.8
GABA (ug/g) 292.6 ± 41.5 200.3 ± 49.8 602.7 ± 82.8## 730.1 ± 99.2##
GLU (ug/g) 0.4 ± 0.06 0.3 ± 0.05 0.5 ± 0.06 0.7 ± 0.07
GLN (ug/g) 178.2 ± 25.2 132.0 ± 35.8 356.7 ± 41.5# 501.0 ± 64.2##
  1. Data are means ± SEM (n = 6–7). #p < 0.05, ##p < 0.01 compared to virgin group; *p < 0.05, **p < 0.01compared to control group