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Table 4 Receiver operator curve for Non–High-Density lipoprotein fractions for identifying children with MetS

From: Are non-high–density lipoprotein fractions associated with pediatric metabolic syndrome? The CASPIAN-V study

Variable Age-sex group Cut-off points (95% CI) Sensitivity (95% CI) Specificity (95% CI) AUC
Non-HDL-C (mg/dl) 7–10 y
Boy 163 (96.29, 227.70) 0.69 (0.585, 0.807) 0.73 (0.48, 0.97) 0.71
Girl 104.5 (88.21, 119.78) 0.71 (0.47, 0.95) 0.50 (0.28, 0.70) 0.60
Total 104.5 (73.99, 134.00) 0.60 (0.28, 0.91) 0.50 (0.14, 0.85) 0.55
11–14 y
Boy 119.5 (107.00,130.99) 0.54 (0.34,0.74) 0.73 (0.59,0.85) 0.64
Girl 116.5 (77.57,154.42) 0.49 (0.10, 0.86) 0.65 (0.21, 1.07) 0.57
Total 116.5 (111.38, 120.61) 0.53 (0.37, 0.68) 0.67 (0.57, 0.76) 0.60
15–18 y
Boy 101.5 (81.67,120.32) 0.91 (0.66,1.16) 0.51 (0.27,0.73) 0.71
Girl 115.5 (75.49, 154.50) 0.54 (0.07, 1.00) 0.64 (0.14, 1.14) 0.59
Total 104.5 (83.66, 124.33) 0.79 (0.52, 1.06) 0.52 (0.25, 0.78) 0.65
7-18y
Boy 119.5 (103.37, 134.62) 0.49 (0.26, 0.71) 0.73 (0.50, 0.95) 0.61
Girl 115.5 (88.58, 141.41) 0.49 (0.18, 0.78) 0.64 (0.25, 1.01) 0.56
Total 120.5 (105.33, 134.66) 0.44 (0.22, 0.65) 0.73 (0.52, 0.93) 0.58
Diff-C (mg/dl) 7–10 y
Boy 19.9 (17.47, 22.12) 0.78 (0.60, 0.95) 0.78 (0.72, 0.83) 0.78
Girl 20.7 (15.94, 25.25) 0.89 (0.75, 1.00) 0.78 (0.66, 0.89) 0.84
Total 19.9 (18.88,20.71) 0.84 (0.73,0.93) 0.77 (0.72,0.81) 0.80
11–14 y
Boy 19.9 (18.26, 21.33) 0.83 (0.71, 0.93) 0.77 (0.72, 0.81) 0.80
Girl 19.9 (18.18, 21.41) 0.82 (0.69, 0.94) 0.73 (0.64, 0.82) 0.78
Total 19.9 (18.41, 21.18) 0.82 (0.74,0.90) 0.75 (0.71,0.78) 0.79
15–18 y
Boy 19.9 (18.05, 21.54) 0.91 (0.83, 0.99) 0.74 (0.67, 0.80) 0.83
Girl 20.5 (15.45, 25.34) 0.92 (0.75, 1.08) 0.76 (0.68, 0.84) 0.84
Total 19.9 (19.16,20.43) 0.92 (0.84,0.99) 0.74 (0.70,0.77) 0.83
7–18 y
Boy 19.9 (19.26,20.33) 0.84 (0.76,0.91) 0.76 (0.73,0.79) 0.80
Girl 19.9 (19.37,20.22) 0.86 (0.78,0.93) 0.74 (0.70,0.78) 0.80
Total 19.9 (19.76, 19.83) 0.85 (0.79,0.90) 0.75 (0.74,0.76) 0.80
Atherogenic index 7–10 y
Boy 2.53 (1.83,3.23) 0.70 (0.52,0.88) 0.83 (0.70,0.95) 0.77
Girl 2.57 (2.03,3.10) 0.93 (0.83,1.02) 0.81 (0.69,0.92) 0.87
Total 2.53 (2.10,2.96) 0.82 (0.72,0.90) 0.81 (0.71,0.91) 0.82
11–14 y
Boy 2.58 (2.37,2.78) 0.80 (0.70,0.90) 0.82 (0.78,0.86) 0.81
Girl 2.54 (1.96,3.11) 0.79 (0.65,0.93) 0.77 (0.61,0.93) 0.78
Total 2.54 (2.25,2.83) 0.80 (0.70,0.89) 0.80 (0.72,0.87) 0.80
15–18 y
Boy 2.48 (2.04,2.91) 0.89 (0.75,1.01) 0.75 (0.65,0.83) 0.82
Girl 2.73 (2.24,3.22) 0.92 (0.79,1.05) 0.82 (0.75,0.88) 0.87
Total 2.48 (2.17,2.78) 0.90 (0.79,.99) 0.76 (0.69,0.82) 0.83
7–18 y
Boy 2.53 (2.35,2.71) 0.80 (0.71,0.88) 0.80 (0.76,0.83) 0.80
Girl 2.54 (2.19,2.89) 0.86 (0.77,0.94) 0.79 (0.71,0.86) 0.83
Total 2.53 (2.41,2.65) 0.82 (0.76,0.88) 0.79 (0.76,0.82) 0.81
  1. CI confidence interval, AUC area under curve, shown as percentage
  2. Non–HDL-C concentration was calculated by subtracting HDL-C value from total cholesterol concentration. Diff-C was defined as the difference between total amount of non-HDL cholesterol and LDL-C (Diff-C = [non-HDL-C]-[LDL-C]). Atherogenic index as the ratio between TG and HDL-C concentrations
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