Skip to main content

Table 3 Factors associated with overall survival of patients with HCC in the absence of cirrhosis

From: Effect of serum triglyceride level on the prognosis of patients with hepatocellular carcinoma in the absence of cirrhosis

Variables Univariate analysis Multivariate analysis
HR 95%CI P values HR 95%CI P values
Age > 50 yrs 1.01 0.99–1.03 0.283    
Gender (male) 0.85 0.51–1.40 0.517    
Family history of HCC 1.16 0.51–2.67 0.72    
Alcohol abuse 1.76 1.18–2.63 0.006    
Diabetes 1.41 0.83–2.38 0.202    
Hypertension 0.85 0.53–1.36 0.507    
Hyperlipidemia 0.98 0.54–1.80 0.949    
Etiology
 HBV 0.62 0.39–0.97 0.037    
 HCV 1.8 1.08–3.02 0.025    
 Alcohol abuse 1.54 0.71–3.32 0.272    
 NAFLD 2.07 0.65–6.54 0.216    
HBV-DNA ≥ 500 IU/ml 1.36 0.88–2.10 0.164    
Antiviral therapy 0.52 0.32–0.86 0.011 0.53 0.32–0.89 0.015
PVTT at baseline 6.17 3.32–11.46 < 0.0001 3.4 1.73–6.67 < 0.0001
Leukocyte counts 1.05 0.96–1.14 0.332    
NLR 0.99 0.95–1.03 0.675    
Platelets (109/L) 1.002 0.999–1.005 0.193    
AST (U/L) 1.002 0.998–1.006 0.403    
Totall Bilirubin (umol/L) 1.005 1.002–1.008 0.001    
Albumin (g/L) 0.939 0.902–0.978 0.002    
γ-GGT (U/L) 1.006 1.004–1.008 < 0.0001 1.006 1.004–1.009 < 0.0001
Triglyceride (mmol/L) 0.7 0.44–1.11 0.128 0.51 0.29–0.89 0.017
PTA (%) 0.986 0.973–0.999 0.032    
AFP ≥ 400 ng/ml 2.235 1.469–3.40 < 0.0001    
Tumor size > 5 cm 3.99 2.65–6.02 < 0.0001 2.79 1.72–4.50 < 0.0001
Tumor numbers ≥2 2.3 1.53–3.46 < 0.0001    
CRP (mg/L) 1.008 1.003–1.013 0.002    
  1. Abbreviations: CRP C-reactive protein