Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty liver disease

Table 2 Clinical and biochemical characteristics of the CN, NF and OF groups

	CN group	NF group	OF group	F	P
Age, years	38.63 ± 12.68	46.31 ± 11.61	39.05 ± 11.14	2.59	0.08
BMI,^† Kg/m²	24.31 ± 4.14	25.45 ± 2.82	31.78 ± 2.17**ΔΔ	30.95	0.00
Waist,^† cm	85.45 ± 14.67	91.26 ± 10.78	112.89 ± 6.76**ΔΔ	31.81	0.00
SBP,^† mm Hg	120.59 ± 15.74	138.79 ± 18.58**	141.37 ± 18.90**ΔΔ	8.55	0.001
DBP,^† mm Hg	73.36 ± 12.21	80.74 ± 8.52*	87.26 ± 13.48**	7.32	0.001
ALT,^† U/L	24.09 ± 11.05	29.10 ± 13.34	49.74 ± 36.95**ΔΔ	6.87	0.002
AST,^† U/L	18.77 ± 4.30	20.63 ± 6.90	27.95 ± 14.61**Δ	5.23	0.008
ALP,^† U/L	66.63 ± 14.53	79.26 ± 28.35*	74.68 ± 13.65*	2.15	0.126
rGT,^† U/L	22.64 ± 10.52	38.37 ± 28.40	83.58 ± 61.12*	2.35	0.105
TC,^† mmol/L	4.66 ± 0.88	5.52 ± 1.00**	5.02 ± 0.91	4.38	0.017
TG,^† mmol/L	1.42 ± 0.68	2.21 ± 1.55*	1.73 ± 0.66	3.05	0.055
HDLc,^† mmol/L	1.18 ± 0.20	1.15 ± 0.17	2.05 ± 2.64	2.31	0.109
LDLc,^† mmol/L	1.93 ± 0.46	2.53 ± 0.56**	2.18 ± 0.48Δ	7.51	0.001
FFA,^† mEq/L	0.94 ± 0.24	1.15 ± 0.60	1.06 ± 0.31	1.42	0.25
Glu,^† mmol/L	4.86 ± 0.55	5.72 ± 1.07**	5.59 ± 1.01*	4.97	0.01
INS,^† uIU/ml	8.11 ± 6.17	13.25 ± 8.02*	14.86 ± 8.01**	4.76	0.012
HOMA-IR,^†	1.78 ± 1.41	3.52 ± 2.48**	3.69 ± 2.16**	5.52	0.006

^†Data were expressed as the mean ± SD of 30 people in the CN group, 21 people in the NF group, and 22 people in the OF group. Statistically significant differences between groups were determined using ANOVA (*p < 0.05, **p < 0.01, ***p < 0.001 vs the CN group; ^Δp < 0.05, ^ΔΔp < 0.01 vs the NF group)
ALP Alkaline phosphatase, ALT Alanine transaminase, AST Aspartate transaminase, BMI body mass index, DBP diastolic blood press, FFA free fatty acids, Glu Glucose, HDLc High-density lipoprotein cholesterol, HOMA-IR Homeostasis model assessment of insulin resistance, INS Insulin, LDLc Low-density lipoprotein cholesterol, SBP Systolic blood press, SD standard deviation, TC Total cholesterol, TG Triacylglycerol, rGT gamma-glutamyl transpeptidase

ISSN: 1476-511X