Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty liver disease

Table 3 Correlation of PPARα and its target genes with main clinical parameters in OF group

OF group		SLC	PDK4	PPARα	CPT1B	ACAA2	ACADVL	CPT1A
AC,^†	Pearson Correlation	.112	−.436*	−.383	−.411*	−.131	.303	−.403*
AC,^†	Significant (unilateral)	.324	.031	.053	.040	.297	.104	.044
BMI,^†	Pearson Correlation	.360	−.532**	−.577**	−.512*	−.499*	.450*	−.549**
BMI,^†	Significant (unilateral)	.065	.010	.005	.012	.015	.027	.007
SBP,^†	Pearson Correlation	−.065	−.204	−.175	−.233	−.035	−.051	−.285
SBP,^†	Significant (unilateral)	.396	.201	.236	.168	.443	.417	.118
DBP,^†	Pearson Correlation	.245	−.573**	−.561**	−.628**	−.395*	.270	−.677**
DBP,^†	Significant (unilateral)	.156	.005	.006	.002	.047	.132	.001
ALT,^†	Pearson Correlation	−.373	−.486*	−.365	−.387	−.228	−.177	−.382
ALT,^†	Significant (unilateral)	.058	.018	.062	.051	.173	.235	.053
GLU,^†	Pearson Correlation	−.264	.425*	.484*	.388	.382	−.530**	.385
GLU,^†	Significant (unilateral)	.137	.035	.018	.050	.053	.010	.052
INS,^†	Pearson Correlation	−.432*	.224	.422*	.291	.441*	−.349	.326
INS,^†	Significant (unilateral)	.032	.178	.036	.114	.029	.071	.086
HOMA -IR,^†	Pearson Correlation	−.444*	.342	.546**	.377	.538**	−.445*	.424*
HOMA -IR,^†	Significant (unilateral)	.028	.076	.008	.056	.009	.028	.035

^†In the OF group, the correlation between PPARα target genes and primary clinical parameters were determined using the Spearman rank test (*p < 0.05,**p < 0.01)
AC Abdominal circumference, ALT Alanine transaminase, BMI body mass index, DBP diastolic blood press, Glu Glucose, HOMA-IR Homeostasis model assessment of insulin resistance, INS Insulin, SBP Systolic blood press

ISSN: 1476-511X