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Table 3 Correlation of PPARα and its target genes with main clinical parameters in OF group

From: Changes in peroxisome proliferator-activated receptor alpha target gene expression in peripheral blood mononuclear cells associated with non-alcoholic fatty liver disease

OF group   SLC PDK4 PPARα CPT1B ACAA2 ACADVL CPT1A
AC, Pearson Correlation .112 −.436* −.383 −.411* −.131 .303 −.403*
Significant (unilateral) .324 .031 .053 .040 .297 .104 .044
BMI, Pearson Correlation .360 −.532** −.577** −.512* −.499* .450* −.549**
Significant (unilateral) .065 .010 .005 .012 .015 .027 .007
SBP, Pearson Correlation −.065 −.204 −.175 −.233 −.035 −.051 −.285
Significant (unilateral) .396 .201 .236 .168 .443 .417 .118
DBP, Pearson Correlation .245 −.573** −.561** −.628** −.395* .270 −.677**
Significant (unilateral) .156 .005 .006 .002 .047 .132 .001
ALT, Pearson Correlation −.373 −.486* −.365 −.387 −.228 −.177 −.382
Significant (unilateral) .058 .018 .062 .051 .173 .235 .053
GLU, Pearson Correlation −.264 .425* .484* .388 .382 −.530** .385
Significant (unilateral) .137 .035 .018 .050 .053 .010 .052
INS, Pearson Correlation −.432* .224 .422* .291 .441* −.349 .326
Significant (unilateral) .032 .178 .036 .114 .029 .071 .086
HOMA
-IR,
Pearson Correlation −.444* .342 .546** .377 .538** −.445* .424*
Significant (unilateral) .028 .076 .008 .056 .009 .028 .035
  1. In the OF group, the correlation between PPARα target genes and primary clinical parameters were determined using the Spearman rank test (*p < 0.05,**p < 0.01)
  2. AC Abdominal circumference, ALT Alanine transaminase, BMI body mass index, DBP diastolic blood press, Glu Glucose, HOMA-IR Homeostasis model assessment of insulin resistance, INS Insulin, SBP Systolic blood press