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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Chlorogenic acid against palmitic acid in endoplasmic reticulum stress-mediated apoptosis resulting in protective effect of primary rat hepatocytes

Fig. 2

Chlorogenic acid protects primary rat hepatocytes against ER stress induced by palmitic acid. a Western blot and (b) densitometric analysis demonstrating the reduction of palmitic acid (PA)-induced GRP78 expression by 1 or 5 μmol/l chlorogenic acid (CGA) after 16 h. a Western blot and (c) densitometric analysis of GRP94 expression after 16 h incubation of cells with 250 μmol/l palmitic acid (PA) in presence of 1 or 5 μmol/l chlorogenic acid (CGA). a Western blot and (d) densitometric analysis demonstrating the reduction of palmitic acid (PA)-induced CHOP expression by 1 or 5 μmol/l chlorogenic acid (CGA) after 16 h. Data represent mean ± S.E.M., n = 5, *P<0.05 vs. LG, low glucose control (0 μmol/l palmitic acid), **P<0.05 vs. palmitic acid only cells

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Lipids in Health and Disease

ISSN: 1476-511X