Early postoperative changes of sphingomyelins and ceramides after laparoscopic sleeve gastrectomy

Table 2 Levels of serum sphingomyelins

Control Group (n = 15)				Sleeve Gastrectomy Group (n = 20)
Sphingolipids (μg/ml)	Preop	Po Day 1	Po Day 30	Preop	Po Day 1	Po Day 30
16:0 SM (d18:1/16:0)	217,16 ± 19,10	225,40 ± 27,36	267,25 ± 24,50	279,88 ± 19,43^a	223,68 ± 20,34^b,c	262,14 ± 17,85
18:0 SM (d18:1/18:0)	100,24 ± 9,67	113,84 ± 13,51	103,51 ± 14,02	131,97 ± 11,91^a	126,93 ± 11,10	154,90 ± 9,83^d
24:0 SM (d18:1/24:0)	75,94 ± 7,19	88,93 ± 12,62	113,06 ± 9,16^e	98,64 ± 10,59	60,57 ± 8,14^f	58,54 ± 6,84^f,d

Values are mean ± SEM. Preop, preoperation; Po, postoperation. 16:0 SM (d18:1/16:0), N-palmitoyl-D-erythrosphingosylphosphorylcholine; 18:0 SM (d18:1/18:0), N-stearoyl-D-erythro-sphingosylphosphorylcholine; 24:0 SM (d18:1/24:0), N-lignoceroyl-D-erythro-sphingosylphosphorylcholine
a, p < 0,05 vs. control Preop. Statistical analysis was done by t-test
b, p = 0,015 vs. sleeve gastrectomy Preop. Statistical analysis was done by paired t-test
c, p = 0,006 vs. sleeve gastrectomy Po day 30. Statistical analysis was done by paired t-test
d, p < 0,01 vs. control Po day 30. Statistical analysis was done by t-test
e, p < 0,001 vs. control Preop. Statistical analysis was done by paired t-test
f, p < 0,001 vs. sleeve gastrectomy Preop. Statistical analysis was done by paired t-test

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