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Table 1 Baseline Characteristics of participants

From: AST to ALT ratio and arterial stiffness in non-fatty liver Japanese population:a secondary analysis based on a cross-sectional study

AST/ALT

Q1

Q2

Q3

Q4

P-value

P-value*

N

89

138

207

212

  

AGE (years, mean ± sd)

49.0 ± 9.7

50.7 ± 8.6

51.7 ± 9.5

52.7 ± 10.0

0.017

0.015

BMI (kg/m2, mean ± sd)

23.1 ± 2.2

22.5 ± 2.5

22.0 ± 2.4

21.4 ± 2.3

< 0.001

< 0.001

SBP (mmHg, mean ± sd)

120.7 ± 16.3

118.8 ± 13.0

116.8 ± 15.3

116.0 ± 13.8

0.040

0.071

DBP (mmHg, mean ± sd)

76.5 ± 10.0

76.1 ± 9.3

73.6 ± 9.9

72.7 ± 9.7

0.001

< 0.001

GGT (IU/L, mean ± sd)

21.0(17.0–40.0)

21.5(15.0–33.0)

16.0(12.0–20.0)

14.0 (11.0–18.0)

< 0.001

< 0.001

Uric acid (mg/dl, mean ± sd)

5.2 ± 1.2

5.5 ± 1.4

4.7 ± 1.2

4.8 ± 1.2

< 0.001

< 0.001

Fasting glucose (mg/dL, mean ± sd)

98.2 ± 9.4

96.8 ± 9.6

95.6 ± 9.0

92.4 ± 7.5

< 0.001

< 0.001

TC (mg/dL, mean ± sd)

206.4 ± 32.5

207.1 ± 35.7

206.1 ± 35.2

207.8 ± 36.2

0.970

0.935

LDL (mg/dL, mean ± sd)

127.1 ± 29.9

125.3 ± 31.2

123.4 ± 30.2

122.6 ± 32.1

0.646

0.594

eGFR(mL/min/1.73 m2, mean ± sd)

71.0 ± 12.2

70.1 ± 11.3

71.9 ± 11.7

70.5 ± 12.9

0.498

0.434

baPWV (cm/s, mean ± sd)

1403.4 ± 270.1

1383.0 ± 216.9

1380.7 ± 225.9

1393.5 ± 250.3

0.866

0.844

SEX (n,%)

    

< 0.001

 male

77 (86.5%)

105 (76.1%)

103 (49.8%)

87 (41.0%)

  

 female

12 (13.5%)

33 (23.9%)

104 (50.2%)

125 (59.0%)

  

Current smokig (n,%)

    

< 0.001

 none

62 (69.7%)

98 (71.0%)

170 (82.1%)

187 (88.2%)

  

 Current

27 (30.3%)

40 (29.0%)

37 (17.9%)

25 (11.8%)

  

Ex-Smoking (n,%)

    

< 0.001

 no

32 (36.0%)

60 (43.5%)

125 (60.4%)

129 (60.8%)

  

 yes

57 (64.0%)

78 (56.5%)

82 (39.6%)

83 (39.2%)

  

Regular Exercise (> 1 week) (n,%)

    

0.039

 No

78 (87.6%)

104 (77.0%)

155 (77.1%)

151 (72.2%)

  

 Yes

11 (12.4%)

31 (23.0%)

46 (22.9%)

58 (27.8%)

  

Post-Menopausal (n,%)

    

0.692

 no

7 (58.3%)

17 (51.5%)

45 (43.3%)

57 (45.6%)

  

 yes

5 (41.7%)

16 (48.5%)

59 (56.7%)

68 (54.4%)

  

Alcohol consumption (n,%)

    

0.043

  < 40 (g/week)

59 (66.3%)

72 (52.9%)

148 (71.8%)

140 (66.7%)

  

  ≤ 40–140

16 (18.0%)

29 (21.3%)

31 (15.0%)

31 (14.8%)

  

  > 140–280

4 (4.5%)

18 (13.2%)

15 (7.3%)

20 (9.5%)

  

  > 280

10 (11.2%)

17 (12.5%)

12 (5.8%)

19 (9.0%)

  

 ABI

1.2 ± 0.1

1.2 ± 0.1

1.2 ± 0.1

1.3 ± 0.8

0.055

< 0.001

  1. ALT alanine aminotransferase, AST aspartate transaminase, baPWV brachial-ankle pulse wave velocity, BMI body mass index, eGFR estimated glomerular filtration rate, GGT γ-glutamyltranspeptidase, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, SBP systolic pressure, DBP Diastole pressure, Tg triglyceride, TC total cholesterol, ABI ankle-brachial index