Table 1 Main characteristics of the studies for polymorphisms included in the meta-analysis
First author | Year | Ethnicity | Case/ Control | DM | Mean age | Gender (M:F) | Duration (years) | Creatinine (μmol/l) | Urea nitrogen (mmol/l) | Plasma glucose (mmol/l) | HbA1c (mmol/mol) | HDL (mg/dL) | LDL (mg/dL) | Uaer (mg /24 h) | Quality |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ma | 2008 | GoKinD | 662/620 | T1D | 44 ± 7/ 40 ± 8 | 350/312: 251/369 | 31 ± 8/ 26 ± 8 | 37.45 ± 33.51/ 15.39 ± 2.74 | NA | NA | NA | 53.6 ± 17.5/ 59.0 ± 15.8 | NA | NA | 9 |
Ma | 2006 | Swedish | 196/236 | T1D | 46 ± 12/ 44 ± 12 | 103/93: 105/131 | 34 ± 12/ 29 ± 10 | NA | NA | NA | 7.4 ± 1.35/ 7.0 ± 1.15 | NA | NA | NA | 9 |
Seman | 2015 | Malaysia | 303/277 | T2D | 57 ± 10/ 56 ± 10 | 166/137: 120/157 | 13 ± 8/ 13 ± 8 | 202.3 ± 171.2/ 90.8 ± 71.1 | NA | 6.4 ± 0.7/ 5.3 ± 2.1 | 8.8 ± 2.2/ 8.1 ± 1.9 | NA | NA | NA | 6 |
Ren | 2015 | Chinese | 402/385 | T2D | 63.8 ± 11.4/ 66.4 ± 11.2 | 204/198: 191/194 | 14.3 ± 6.8/ 15.6 ± 5.9 | 69.8 ± 43.6/ 76.6 ± 55.9 | 6.1 ± 2.5/ 6.2 ± 2.7 | 8.9 ± 3.6 /7.5 ± 2.7 | 68.4 ± 22.1/ 64.0 ± 18.0 | 1.3 ± 0.5/ 1.3 ± 0.8 | 2.6 ± 0.8/ 2.5 ± 0.8 | NA | 8 |
Chen | 2010 | Chinese | 94/95 | T2D | 57.69 ± 9.72/ 55.72 ± 9.98 | 42/52: 44/51 | 85.85 ± 79.76/ 83.15 ± 50.85 | NA | NA | NA | NA | NA | NA | NA | 8 |
wang | 2006 | Chinese | 110/100 | T2D | 61.7 ± 7.1/ 60.2 ± 6.9 | 56/54: 50/50 | 10.2 ± 5.9/ 9.7 ± 6.1 | NA | NA | NA | NA | 0.92 ± 0.29/ 1.11 ± 0.21 | 3.61 ± 0.60/ 3.10 ± 0.67 | 1390(990–2560)/< 30 | 7 |
Oguz | 2015 | Turkish | 138/138 | NC | 54.77 ± 2.49/ 50.1 ± 8 | 46/92: 49/89 | na | NA | NA | 170 ± 21.2/89 ± 8.7 | 11.36 ± 1.8/ 5.5 ± 0.4 | 39.18 ± 13.8/ 51.65 ± 4.2 | 130.00 ± 20/ 96.60 ± 22.77 | NA | 6 |