Skip to main content

Table 2 Logistic regression analysis of lipid profiles and NSCLC risk

From: Dyslipidemia and non-small cell lung cancer risk in Chinese population: a case-control study

Variable

Univariate

 

Multivariablea

 

OR

95% CI

P

OR

95%CI

P

BMI

  ≤ 25

1

  

1

  

  > 25

0.893

0.666–1.198

0.451

0.709

0.500–1.004

0.053

Smoking status

 No

1

  

1

  

 Ever/current

6.583

4.315–10.043

P < 0.001

15.979

8.880–28.752

P < 0.001

Alcohol consumption

 No

1

  

1

  

 Yes

1.031

0.733–1.451

0.859

0.988

0.686–1.332

0.786

Hypertension

 No

1

  

1

  

 Yes

1.174

0.873–1.580

 

1.077

0.753–1.541

0.684

Diabetes

 No

1

  

1

  

 Yes

1.425

0.802–2.532

0.227

1.175

0.553–2.494

0.675

Statins use

 No

1

  

1

  

 Yes

1.251

0.561–2.789

 

0.692

0.238–2.009

0.499

TC

 Normal (< 5.2)

1

  

1

  

 BH (≥5.2& < 6.2)

0.655

0.335–1.209

0.176

1.363

0.872–2.128

0.174

 High (≥6.2)

0.589

0.302–1.149

0.120

1.488

0.878–2.521

0.115

LDL-C

 Normal (< 3.4)

1

  

1

  

 BH (≥3.4& < 4.1)

1.125

0.659–1.920

 

0.647

0.293–1.427

0.281

 High (≥4.1)

0.588

0.139–2.476

 

0.198

0.029–1.364

0.100

HDL-C

 Low (< 1.0)

1

  

1

  

 Normal (≥1.0& < 1.5)

0.337

0.242–0.468

P < 0.001

0.320

0.218–0.470

P < 0.001

 High (≥1.5)

0.288

0.185–0.448

P < 0.001

0.233

0.134–0.407

P < 0.001

TG

 Normal (< 1.7)

1

  

1

  

 BH (≥1.7& < 2.3)

1.395

0.977–1.993

0.067

1.352

0.898–2.036

0.149

 High (≥2.3)

1.541

1.072–2.215

0.019

1.052

0.671–1.649

0.826

  1. Abbreviations: BH borderline high, BMI body mass index, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TG triglyceride, NSCLC non-small cell lung cancer
  2. a Multivariable-adjusted model: The individual components of the metabolic syndrome have been mutually adjusted, age, sex, smoking status, hypertension, body mass index, and diabetes