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Table 1 Meta-analysis between the PON1 rs662 polymorphism and Ox-LDL levels

From: Associations of the PON1 rs662 polymorphism with circulating oxidized low-density lipoprotein and lipid levels: a systematic review and meta-analysis

Groups or subgroups

Comparisons (Subjects)

SMD (95% CI)

P Heterogeneity

P SMD

Ox-LDL

 All

13 (1369)

0.23 (0.10–0.36)

< 0.01

< 0.01

 Studies in HWE

3 (426)

0.32 (0.12–0.53)

< 0.01

< 0.01

  Caucasian

2 (345)

−0.16 (− 0.37–0.06)

0.34

0.15

  Asian

11 (1024)

0.44 (0.28–0.60)

< 0.01

< 0.01

  CHD

3 (274)

0.39 (0.12–0.66)

< 0.01

< 0.01

  Healthy or control

4 (518)

0.03 (−0.16–0.22)

0.63

0.74

  1. PON1 Paraoxonase 1 gene, SMD standardized mean difference, 95% CI 95% confidence interval, HWE Hardy-Weinberg equilibrium, Ox-LDL oxidized low density lipoprotein, CHD coronary heart disease