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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolic active tissues

Fig. 1

ABC transporter gene expression in liver, kidney and white adipose tissue of 6-month-old Abcc6−/− mice. Normalized relative gene expression level of various ABC transporters in the (a) liver (b) kidney and (c) WAT of 6-month-old ± 2 weeks male and female WT (liver: n = 25; kidney: n = 25; WAT: n = 21, respectively) and Abcc6−/− mice (liver: n = 22; kidney: n = 23; WAT: n = 18, respectively) by qRT-PCR. Relative mRNA expression of ABC transporter members belonging to a, b, c, d and g subfamily. Data are presented as fold change of mean ± SEM relative to samples of age-matched WT. Statistically significant differences were analyzed using unpaired, two-tailed Student’s t-test and are indicated in the following manner: * p ≤ 0.05; ** p ≤ 0.01; *** p ≤ 0.001

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