Fig. 3

Forest plot of relationships between serum lipid parameters and cognitive impairment in the total population with multivariate analysis (model 1, 2, 3 and 4). High TC, high LDL-C, low HDL-C and high TG were treated as binary data (yes or no) in model 1 and 2. In model 3, TC, LDL-C, HDL-C and TG were transformed into continuous variables. In model 1, the analysis was corrected for gender, age, and years of education. Model 2 was adjusted for the covariates included in model 1 as well as for tobacco use, alcohol consumption, lack of physical activity, CHD, MAP, BMI, FBG. In model 3, the confounding variables considered were the same as those considered in model 2. Model 4 was adjusted for the covariates included in model 2 plus the interaction terms gender by age by serum lipids. Abbreviations: OR, odds ratio; CI, confidence interval; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; TG, triglycerides; CHD, coronary heart disease; MAP, mean arterial pressure; BMI, body mass index; FBG, fasting blood glucose