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Table 1 Demographic and clinical characteristics of the participants (n = 1762)

From: The gender- and age- dependent relationships between serum lipids and cognitive impairment: a cross-sectional study in a rural area of Xi’an, China

Variables

Total (n = 1762)

Normal serum lipids(n = 875)

Dyslipidemia (n = 887)

P

Male [n(%)]

714(40.5)

364(41.6)

350(39.5)

0.360

Age [Mean(SD),year]

55.48(9.95)

54.60(10.03)

56.34(9.80)

< 0.001

Formal Education [n(%)]

   

0.009

 Uneducated

224(12.7)

90(10.3)

134(15.1)

 

 Primary school

508(28.8)

263(30.1)

245(27.6)

 

 High school or above

1030(58.5)

522(59.7)

508(57.3)

 

Education years [Median(P25, P75), y]

7(4.0,8.0)

7(4.3,8.0)

7(4.0,8.0)

0.042

Marital status [n(%)]

   

0.054

 Married

1606(91.1)

809(92.5)

797(89.9)

 

 Others

156(8.9)

66(7.5)

90(10.1)

 

Tobacco use [n(%)]

510(28.9)

267(30.5)

243(27.4)

0.149

Alcohol consumption [n(%)]

251(14.2)

124(14.2)

127(14.3)

0.930

Lack of physical activity [n(%)]

261(14.8)

121(13.8)

140(15.8)

0.248

Comorbidities [n(%)]

 HP

831(47.2)

351(40.1)

480(54.1)

0.001

 DM

210(11.9)

72(8.2)

138(15.6)

0.001

 CHD

38(2.2)

14(1.6)

24(2.7)

0.110

 Atrial fibrillation

10(0.6)

2(0.2)

8(0.9)

0.060

Family history [n(%)]

 HP

542(30.8)

254(29.0)

288(32.5)

0.118

 DM

142(8.1)

69(7.9)

73(8.2)

0.791

 CHD

107(6.1)

57(6.5)

50(5.6)

0.441

 Dyslipidemia

32(1.8)

15(1.7)

17(1.9)

0.751

Physical examination [n(%)]

 Cardiac murmur

28(1.6)

14(1.6)

14(1.6)

0.971

 Arrhythmia

41(2.3)

27(3.1)

14(1.6)

0.136

MAP [Mean(SD), mmHg]

98.46(12.18)

95.99(11.55)

99.78(12.30)

< 0.001

Pulse Rate [Mean(SD)]

75.32(8.85)

75.29(8.64)

75.35(9.06)

0.818

BMI[Mean(SD), kg/m2]

25.28(3.15)

24.67(2.98)

25.88(3.31)

< 0.001

Biochemical examination

 FBG [Median(P25,P75), mmol/L]

5.40(5.06,5.82)

5.33(5.02,5.68)

5.49(5.12,6.00)

< 0.001

 TC [Mean(SD), mmol/L]

5.05(0.99)

4.51(0.63)

5.58(0.99)

< 0.001

 LDL [Mean(SD), mmol/L]

3.32(0.89)

2.86(0.65)

3.78(0.86)

< 0.001

 HDL [Mean(SD), mmol/L]

1.40(0.31)

1.44(0.29)

1.37(0.33)

0.010

 TG [Median(P25,P75), mmol/L]

1.44(1.02,2.00)

1.11(0.89,1.39)

1.99(1.49,2.53)

< 0.001

Cognition

 MMSE [Mean(SD)]

25.66(4.19)

25.87(4.15)

25.46(4.22)

0.038

 Cognitive impairment [n(%)]

226(12.8)

101(11.5)

125(14.1)

0.110

  1. Abbreviations, SD standard deviation; P25, 25% percentile; P75, 75% percentile, HP hypertension, DM diabetes mellitus, CHD coronary heart disease, MAP mean arterial pressure, BMI body mass index, FBG fasting blood glucose, TC total cholesterol, LDL low-density lipoprotein, HDL high-density lipoprotein, TG triglycerides, MMSE Mini-Mental State Examination