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Table 1 Body weight/ adipose tissue weight, biochemistry and other biomarkers

From: Obesity programmed by prenatal dexamethasone and postnatal high-fat diet leads to distinct alterations in nutrition sensory signals and circadian-clock genes in visceral adipose tissue

  VEH DEX VHF DHF H1 H2 H1 × H2
Weight (g) 666.33 ± 18.70 668.00 ± 29.50 763.33 ± 45.42 942.17 ± 61.84*#† p = 0.045 p < 0.001 p = 0.048
Retroperitoneal fat (g) 13.96 ± 1.77 13.17 ± 1.36 28.95 ± 4.53* 48.50 ± 4.47*#† p = 0.012 p < 0.001 p = 0.007
Subcutaneous fat (g) 26.78 ± 2.65 30.72 ± 3.27 56.42 ± 7.36 79.25 ± 9.91 NS p < 0.001 NS
Mesenteric fat (g) 5.76 ± 0.93 5.58 ± 0.68 9.17 ± 1.54 13.91 ± 2.12 NS p = 0.001 NS
Epididymal fat (g) 7.35 ± 0.41 8.05 ± 0.17 18.05 ± 1.46 21.42 ± 1.65 NS p < 0.001 NS
AST (U/L) 128.25 ± 45.53 97.40 ± 9.37 146.33 ± 11.32 248.50 ± 28.92#† NS p = 0.004 p = 0.018
ALT (U/L) 85.75 ± 52.12 44.80 ± 2.46 78.17 ± 11.58 156.67 ± 9.65#† NS p = 0.026 p = 0.012
T-Cholesterol (mg/dL) 88.50 ± 10.74 107.40 ± 17.72 81.17 ± 5.34 63.50 ± 5.49 NS p = 0.025 NS
Triglyceride (mg/dL) 104.75 ± 5.20 136.60 ± 30.76 54.00 ± 6.67 57.67 ± 8.64 NS p = 0.001 NS
ALK-P (U/L) 65.50 ± 11.30 55.80 ± 3.73 49.00 ± 4.68 62.67 ± 7.54 NS NS NS
Leptin (ng/ml) 2.66 ± 0.30 2.58 ± 0.99 4.62 ± 0.48 4.39 ± 0.33 NS p < 0.001 NS
TNFα (pg/ml) 7.81 ± 0.48 8.68 ± 0.18 11.29 ± 0.14 11.36 ± 0.54 NS p < 0.001 NS
VEGF (pg/ml) 15.21 ± 0.24 15.51 ± 0.29 16.53 ± 0.23 16.47 ± 0.28 NS p < 0.001 NS
  1. AST aspartate transaminase, ALT alanine aminotransferase, ALK-P Alkaline phosphatase, VEGF vascular endothelial growth factor, VEH prenatal saline vehicle /postnatal normal diet group, DEX prenatal dexamethasone exposure /postnatal normal diet group, VHF prenatal saline vehicle /postnatal high fat diet group, DHF prenatal dexamethasone exposure /postnatal high-fat diet group. * as compared with VEH, p < 0.05; # as compared with DEX, p < 0.05; † as compared with VHF, p < 0.05