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Table 2 Univariate analysis of possible influencing factors of the risk of EBB-induced bleeding

From: Non-linear association of plasma level of high-density lipoprotein cholesterol with endobronchial biopsy bleeding in patients with lung cancer

Variables EBB-induced Bleeding
OR (95% CI) P value
Age (year) 1.01 (0.99, 1.03) 0.2029
Sex
 Female Ref.  
 Man 1.33 (0.89, 1.98) 0.1609
Smoking
 No Ref.  
 Yes 1.45 (1.03, 2.04) 0.0337
Location of lesion
 Central airway Ref.  
 Peripheral bronchi 0.32 (0.20, 0.51) < 0.0001
Stage
 Early Ref.  
 Advanced 1.87 (1.35, 2.60) 0.0002
Histological type
 Adenocarcinoma Ref.  
 Squamous cell carcinoma 2.63 (1.73, 4.01) < 0.0001
 SCLC 2.14 (1.27, 3.61) 0.0043
 Others 2.20 (1.00, 4.82) 0.0488
COPD
 No Ref.  
 Yes 1.05 (0.55, 2.01) 0.8727
Hypertension
 No Ref.  
 Yes 1.11 (0.76, 1.61) 0.5995
Diabetes
 No Ref.  
 Yes 0.89 (0.42, 1.88) 0.7575
CHD
 No Ref.  
 Yes 1.14 (0.46, 2.84) 0.7736
 Triglyceride (mmol/L) 0.80 (0.62, 1.04) 0.1018
 TC (mmol/L) 0.93 (0.78, 1.11) 0.4113
 HDL-C (mmol/L) 0.56 (0.34, 0.94) 0.0270
 LDL-C (mmol/L) 0.89 (0.71, 1.11) 0.3031
 Apo E (mg/dL) 0.91 (0.82, 1.02) 0.1153
 Apo B (g/L) 0.80 (0.45, 1.42) 0.4421
 Homocysteine (μmol/L) 1.00 (0.98, 1.02) 0.8840
 WBC (×109/L) 1.03 (0.98, 1.08) 0.2477
 Neutrophils (×109/L) 1.04 (0.99, 1.10) 0.0937
 Hemoglobin (g/L) 1.00 (0.99, 1.01) 0.4135
 Platelets (×109/L) 1.00 (1.00, 1.00) 0.2392
 CRP (mg/L) 1.01 (1.00, 1.01) 0.0173
 PT (S) 0.93 (0.84, 1.02) 0.1220
 APTT (S) 0.96 (0.94, 0.99) 0.0180
 ALT (IU/L) 1.00 (0.99, 1.01) 0.8181
 AST (IU/L) 1.00 (0.99, 1.01) 0.9365
  1. EBB endobronchial biopsy; SCLC small-cell lung carcinoma; COPD Chronic obstructive pulmonary disease; CHD coronary heart disease; TC total cholesterol; HDL-C high density lipoprotein cholesterol; LDL-C low density lipoprotein cholesterol; Apo, apolipoprotein; WBC white blood cell; CRP C-reactive protein; PT prothrombin time; APTT activated partial thromboplastin time; ALT alanine aminotransferase; AST aspartate aminotransferase