Non-linear association of plasma level of high-density lipoprotein cholesterol with endobronchial biopsy bleeding in patients with lung cancer

Table 3 Multivariate regression analysis of HDL-C with the risk of EBB-induced bleeding

HDL-C (mmol/L)	EBB-induced bleeding OR (95% CI) P-value
HDL-C (mmol/L)	Non-adjust	Adjust I^a	Adjust II^b
< 1.5	Ref.	Ref.	Ref.
1.5–2.0	0.35 (0.19, 0.64) 0.0007	0.38 (0.20, 0.71) 0.0026	0.39 (0.20, 0.74) 0.0042
≧2.0	1.55 (0.54, 4.48) 0.4187	1.95 (0.65, 5.88) 0.2339	1.63 (0.51, 5.22) 0.4107

^aAdjust I adjust for: smoking, histological type, stage of cancer, triglyceride, PT, APTT and CRP
^bAdjust II adjust for: sex, age, smoking, location of lesion, histological type, stage of cancer, triglyceride, apolipoprotein E, PT, APTT, neutrophils and CRP. EBB, endobronchial biopsy; HDL-C, high density lipoprotein cholesterol; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein

ISSN: 1476-511X