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Table 3 Multivariate regression analysis of HDL-C with the risk of EBB-induced bleeding

From: Non-linear association of plasma level of high-density lipoprotein cholesterol with endobronchial biopsy bleeding in patients with lung cancer

HDL-C (mmol/L) EBB-induced bleeding OR (95% CI) P-value
Non-adjust Adjust Ia Adjust IIb
<  1.5 Ref. Ref. Ref.
1.5–2.0 0.35 (0.19, 0.64) 0.0007 0.38 (0.20, 0.71) 0.0026 0.39 (0.20, 0.74) 0.0042
2.0 1.55 (0.54, 4.48) 0.4187 1.95 (0.65, 5.88) 0.2339 1.63 (0.51, 5.22) 0.4107
  1. aAdjust I adjust for: smoking, histological type, stage of cancer, triglyceride, PT, APTT and CRP
  2. bAdjust II adjust for: sex, age, smoking, location of lesion, histological type, stage of cancer, triglyceride, apolipoprotein E, PT, APTT, neutrophils and CRP. EBB, endobronchial biopsy; HDL-C, high density lipoprotein cholesterol; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein