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Table 3 Genetic model analysis of the association of six SNPs and MI susceptibility

From: Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population

SNP/group Genotype   χ2 P OR (95% CI)
rs12762303
 Dominant CC+ CT TT 0.10 0.92 0.98 (0.73–1.32)
 Recessive CC CT + TT 0.16 0.69 1.14 (0.59–2.18)
 Codominant TT CT 0.06 0.81 0.96 (0.71–1.31)
  CC 0.12 0.72 1.12 (0.58–2.17)
 Overdominant TT + CC CT 0.08 0.76 1.04 (0.77–1.42)
rs12264801
 Dominant AA+GA GG 0.03 0.85 0.97 (0.72–1.31)
 Recessive AA GA + GG 0.87 0.35 0.85 (0.61–1.19)
 Codominant GG GA 0.02 0.88 1.02 (0.74–1.42)
  AA 0.51 0.48 0.87 (0.59–1.28)
 Overdominant GG + AA GA 0.39 0.53 0.91 (0.70–1.21)
rs10507391
 Dominant AA +TA TT 0.17 0.68 1.06 (0.80–1.41)
 Recessive AA TA + TT 0.12 0.91 0.98 (0.64–1.49)
 Codominant TT TA 0.22 0.63 1.07 (0.80–1.44)
  AA 0.00 0.95 1.01 (0.64–1.59)
 Overdominant TT + AA TA 0.23 0.63 0.93 (0.71–1.23)
rs2072512
 Dominant AA +TA TT 0.42 0.51 1.10 (0.83–1.46)
 Recessive AA TA + TT 0.47 0.49 0.79 (1.13)
 Codominant TT TA 0.18 0.66 1.06 (0.79–1.45)
  AA 0.64 0.42 1.18 (0.79–1.75)
 Overdominant TT + AA TA 0.01 0.91 0.98 (0.75–1.30)
rs2540487
 Dominant TT + CT CC 4.36 0.037 0.73 (0.55–0.98)
 Recessive TT CT + CC 0.99 0.32 1.36 (0.74–2.51)
 Codominant CC CT 6.29 0.012 0.68 (0.51–0.92)
  TT 0.31 0.57 1.19 (0.64–2.22)
 Overdominant CC + TT CT 6.97 0.008 a 1.48 (1.11–1.99)
rs2540477
 Dominant GG + AG AA 0.90 0.34 0.84 (0.59–1.20)
 Recessive GG AG + AA 0.16 0.69 0.94 (0.70–1.26)
 Codominant AA AG 0.74 0.38 0.85 (0.58–1.23)
  GG 0.78 0.38 0.83 (0.56–1.25)
 Overdominant AA+GG AG 0.13 0.72 1.05 (0.80–1.39)
  1. SNP, single nucleotide polymorphism; MI, myocardial infarction. A P < 0.01 was considered statistically significant after Bonferroni correction. a P-values < 0.01 are bold