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Table 4 Lipid level and genotype in MI patients and controls

From: Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population

SNP Genotype (Counts) TC TG HDL-C LDL-C CRE FBG
mmol/L mmol/L mmol/L mmol/L μmol/L mmol/L
rs12762303
case TT (270) 4.53 ± 1.13 1.66 ± 1.16 1.28 ± 0.47 2.78 ± 0.86 87.35 ± 31.89 7.36 ± 4.03
CT (111) 4.63 ± 0.85 1.56 ± 0.79 1.26 ± 0.31 2.76 ± 0.78 82.38 ± 26.64 6.31 ± 3.36
CC (20) 4.59 ± 0.94 1.93 ± 1.91 1.29 ± 0.33 2.79 ± 0.70 81.25 ± 23.09 8.67 ± 3.29
P 0.718 0.807 0.890 0.936 0.296 0.008 a
control TT (274) 4.97 ± 0.85 1.71 ± 1.26 1.39 ± 0.40 3.28 ± 0.75 70.82 ± 13.74 6.00 ± 2.05
CT (117) 4.86 ± 0.88 1.57 ± 1.22 1.36 ± 0.29 3.27 ± 0.73 70.01 ± 12.14 5.81 ± 1.59
CC (18) 5.13 ± 0.61 1.64 ± 0.72 1.22 ± 0.23 3.39 ± 0.78 76.57 ± 12.84 5.80 ± 1.78
P 0.409 0.134 0.168 0.481 0.063 0.925
rs12264801
case AA (86) 4.65 ± 0.96 1.71 ± 1.22 1.27 ± 0.45 2.79 ± 0.89 82.11 ± 25.52 7.47 ± 3.22
GA (199) 4.57 ± 1.07 1.71 ± 1.18 1.24 ± 0.30 2.75 ± 0.82 88.13 ± 32.29 6.85 ± 4.21
GG (116) 4.50 ± 1.06 1.49 ± 0.93 1.35 ± 0.57 2.78 ± 0.83 84.09 ± 29.45 7.36 ± 3.65
P 0.737 0.205 0.082 0.990 0.451 0.156
control AA (99) 4.94 ± 0.77 1.63 ± 1.09 1.31 ± 0.26 3.27 ± 0.76 70.92 ± 13.80 5.91 ± 1.93
GA (194) 4.99 ± 0.91 1.73 ± 1.40 1.41 ± 0.40 3.30 ± 0.76 71.08 ± 12.52 5.88 ± 1.76
GG (116) 4.88 ± 0.79 1.58 ± 1.02 1.35 ± 0.37 3.27 ± 0.71 70.38 ± 14.19 6.05 ± 2.16
P 0.253 0.950 0.128 0.891 0.666 0.981
rs10507391
case TT (158) 4.77 ± 1.03 1.73 ± 1.30 1.28 ± 0.33 2.85 ± 0.81 81.90 ± 24.50 7.48 ± 3.91
AT (195) 4.46 ± 1.01 1.64 ± 1.06 1.28 ± 0.51 2.70 ± 0.81 87.82 ± 31.25 7.02 ± 3.81
AA (48) 4.29 ± 1.15 1.41 ± 0.61 1.23 ± 0.31 2.77 ± 1.00 89.35 ± 40.38 6.44 ± 3.85
P 0.006 0.678 0.531 0.165 0.224 0.250
control TT (167) 4.95 ± 0.93 1.58 ± 1.17 1.35 ± 0.31 3.33 ± 0.80 70.83 ± 12.84 5.87 ± 1.93
AT (192) 4.93 ± 0.80 1.69 ± 1.21 1.37 ± 0.40 3.24 ± 0.72 70.64 ± 13.95 6.00 ± 2.02
AA (50) 5.02 ± 0.74 1.84 ± 1.46 1.45 ± 0.40 3.28 ± 0.67 71.68 ± 12.38 5.89 ± 1.45
P 0.708 0.479 0.270 0.677 0.825 0.291
rs2072512
case AA (74) 4.64 ± 1.22 1.65 ± 1.11 1.23 ± 0.34 2.83 ± 0.93 92.85 ± 41.31 7.05 ± 4.00
AT (180) 4.54 ± 1.01 1.57 ± 1.07 1.27 ± 0.32 2.78 ± 0.81 83.11 ± 21.81 7.37 ± 3.79
TT (147) 4.56 ± 1.00 1.74 ± 1.19 1.31 ± 0.56 2.71 ± 0.81 85.19 ± 31.99 6.89 ± 3.89
P 0.530 0.186 0.847 0.769 0.171 0.504
control AA (68) 4.88 ± 0.90 1.53 ± 1.17 1.38 ± 0.40 3.22 ± 0.72 69.85 ± 13.40 5.84 ± 2.08
AT (182) 4.96 ± 0.81 1.67 ± 1.25 1.35 ± 0.30 3.34 ± 0.74 70.49 ± 13.45 5.89 ± 1.95
TT (159) 4.96 ± 0.86 1.71 ± 1.22 1.40 ± 0.42 3.24 ± 0.77 71.67 ± 13.12 6.03 ± 1.81
P 0.245 0.418 0.809 0.329 0.384 0.343
rs2540487
case CC (261) 4.58 ± 1.02 1.70 ± 1.21 1.29 ± 0.45 2.78 ± 0.82 84.94 ± 30.49 7.17 ± 4.09
CT (115) 4.53 ± 1.11 1.54 ± 0.97 1.29 ± 0.38 2.76 ± 0.89 85.09 ± 27.13 7.19 ± 3.60
TT (25) 4.52 ± 1.06 1.62 ± 0.73 1.14 ± 0.39 2.69 ± 0.78 96.00 ± 38.53 6.50 ± 2.22
P 0.713 0.530 0.469 0.900 0.166 0.419
control CC (237) 4.96 ± 0.86 1.70 ± 1.23 1.36 ± 0.35 3.30 ± 0.75 70.82 ± 14.12 6.02 ± 2.00
CT (153) 4.92 ± 0.83 1.65 ± 1.28 1.38 ± 0.39 3.24 ± 0.72 71.63 ± 11.87 5.84 ± 1.81
TT (19) 5.01 ± 0.93 1.33 ± 0.71 1.46 ± 0.29 3.32 ± 0.96 64.79 ± 12.61 5.69 ± 1.76
P 0.496 0.484 0.224 0.615 0.161 0.672
rs2540477
case AA (79) 4.71 ± 1.20 1.71 ± 1.27 1.23 ± 0.32 2.87 ± 0.91 94.05 ± 38.87 7.04 ± 3.64
GA (193) 4.54 ± 0.99 1.61 ± 1.14 1.26 ± 0.33 2.76 ± 0.81 80.42 ± 23.65 7.31 ± 3.40
GG (129) 4.52 ± 1.02 1.66 ± 1.01 1.32 ± 0.58 2.71 ± 0.82 88.39 ± 31.50 6.92 ± 3.80
P 0.367 0.477 0.971 0.508 0.066 0.680
control AA (70) 4.81 ± 0.85 1.51 ± 1.16 1.34 ± 0.38 3.19 ± 0.71 71.56 ± 13.09 5.91 ± 2.20
GA (202) 5.03 ± 0.85 1.65 ± 1.21 1.39 ± 0.35 3.35 ± 0.79 69.74 ± 13.54 5.90 ± 1.89
GG (137) 4.90 ± 0.84 1.77 ± 1.28 1.37 ± 0.38 3.23 ± 0.69 72.10 ± 12.99 6.00 ± 1.81
P 0.073 0.222 0.328 0.154 0.207 0.507
  1. SNP single nucleotide polymorphism, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, CRE creatinine, FBG fasting blood glucose. Results are mean ± SD. Significance (P < 0.05) was determined by the Kruskal–Wallis test. Significant difference, P < 0.0083 after the Bonferroni correction. aP-values < 0.0083 are bold