Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population

Table 5 The P values for interactions of genotypes and age, drinking and smoking, on lipid levels and the risk of CAD

SNP	Factor	TC	TG	HDL-C	LDL-C	CRE	FBG
rs12762303	Drinking	0.022	0.794	0.621	1.57E-4	0.883	0.398
	Smoking	0.452	0.633	0.251	0.213	0.721	0.410
	Age	0.084	0.247	0.633	0.162	0.667	0.415
	Sex	0.115	0.560	0.593	0.200	0.050	0.090
	Hypertension	0.863	0.019	0.050	0.077	0.641	0.481
rs12264801	Drinking	0.582	0.549	0.448	0.503	0.747	0.693
	Smoking	0.798	0.528	0.163	0.838	0.669	0.666
	Age	5.21E-4 ^a	3.47E-4	0.500	0.010	0.071	0.530
	Sex	0.282	0.642	0.110	0.622	0.003	0.003
	Hypertension	0.418	0.006	0.033	0.813	0.135	0.164
rs10507391	Drinking	0.916	0.728	0.633	0.236	0.595	0.961
	Smoking	0.899	0.299	0.082	0.465	0.631	0.803
	Age	1.92E-4	0.006	0.706	2.83E-4	0.321	0.924
	Sex	0.307	0.847	0.090	0.778	0.023	0.034
	Hypertension	0.570	0.038	0.260	0.864	0.044	0.337
rs2072512	Drinking	0.361	0.962	0.629	0.639	0.436	0.915
	Smoking	0.396	0.095	0.240	0.932	0.671	0.259
	Age	0.016	0.012	0.391	0.010	0.051	0.033
	Sex	0.460	0.402	0.505	0.784	0.011	0.019
	Hypertension	0.114	0.002	0.157	0.457	0.930	0.348
rs2540487	Drinking	0.150	0.359	0.988	0.020	0.678	0.941
	Smoking	0.878	0.478	0.174	0.281	0.054	0.468
	Age	0.018	0.010	0.912	0.079	0.178	0.998
	Sex	0.808	0.457	0.900	0.432	0.517	0.191
	Hypertension	0.031	0.001	0.191	0.546	0.261	0.150
rs2540477	Drinking	0.787	0.763	0.898	0.229	0.717	0.926
	Smoking	0.777	0.110	0.147	0.787	0.609	0.533
	Age	0.010	8.73E-6	0.320	0.069	0.095	0.312
	Sex	0.367	0.811	0.228	0.771	0.001	0.071
	Hypertension	0.049	0.002	0.210	0.533	0.677	0.064

SNP single nucleotide polymorphism, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, CRE creatinine, MI myocardial infarction. Significant difference, P < 0.0017 after the Bonferroni correction. ^aP-values < 0.0017 are bold

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