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Table 5 The P values for interactions of genotypes and age, drinking and smoking, on lipid levels and the risk of CAD

From: Genetic variation in the leukotriene pathway is associated with myocardial infarction in the Chinese population

SNP Factor TC TG HDL-C LDL-C CRE FBG
rs12762303 Drinking 0.022 0.794 0.621 1.57E-4 0.883 0.398
Smoking 0.452 0.633 0.251 0.213 0.721 0.410
Age 0.084 0.247 0.633 0.162 0.667 0.415
Sex 0.115 0.560 0.593 0.200 0.050 0.090
Hypertension 0.863 0.019 0.050 0.077 0.641 0.481
rs12264801 Drinking 0.582 0.549 0.448 0.503 0.747 0.693
Smoking 0.798 0.528 0.163 0.838 0.669 0.666
Age 5.21E-4 a 3.47E-4 0.500 0.010 0.071 0.530
Sex 0.282 0.642 0.110 0.622 0.003 0.003
Hypertension 0.418 0.006 0.033 0.813 0.135 0.164
rs10507391 Drinking 0.916 0.728 0.633 0.236 0.595 0.961
Smoking 0.899 0.299 0.082 0.465 0.631 0.803
Age 1.92E-4 0.006 0.706 2.83E-4 0.321 0.924
Sex 0.307 0.847 0.090 0.778 0.023 0.034
Hypertension 0.570 0.038 0.260 0.864 0.044 0.337
rs2072512 Drinking 0.361 0.962 0.629 0.639 0.436 0.915
Smoking 0.396 0.095 0.240 0.932 0.671 0.259
Age 0.016 0.012 0.391 0.010 0.051 0.033
Sex 0.460 0.402 0.505 0.784 0.011 0.019
Hypertension 0.114 0.002 0.157 0.457 0.930 0.348
rs2540487 Drinking 0.150 0.359 0.988 0.020 0.678 0.941
Smoking 0.878 0.478 0.174 0.281 0.054 0.468
Age 0.018 0.010 0.912 0.079 0.178 0.998
Sex 0.808 0.457 0.900 0.432 0.517 0.191
Hypertension 0.031 0.001 0.191 0.546 0.261 0.150
rs2540477 Drinking 0.787 0.763 0.898 0.229 0.717 0.926
Smoking 0.777 0.110 0.147 0.787 0.609 0.533
Age 0.010 8.73E-6 0.320 0.069 0.095 0.312
Sex 0.367 0.811 0.228 0.771 0.001 0.071
Hypertension 0.049 0.002 0.210 0.533 0.677 0.064
  1. SNP single nucleotide polymorphism, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, FBG fasting blood glucose, CRE creatinine, MI myocardial infarction. Significant difference, P < 0.0017 after the Bonferroni correction. aP-values < 0.0017 are bold