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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Exogenous supplement of N-acetylneuraminic acid improves macrophage reverse cholesterol transport in apolipoprotein E-deficient mice

Fig. 1

NANA lowers the TC level and improves reverse cholesterol transport in apoE−/− mice (n = 5). a, NANA lowers the plasma TC level in the apoE−/− mice; b, NANA increases the transfer rate of [3H]-cholesterol from the injected fat-laden macrophages to the plasma of apoE−/− mice; c, [3H]-cholesterol in the liver of apoE−/− mice 48 h after injection; d, [3H]-cholesterol in the faeces of apoE−/− mice. BC: blank control; FF: fenofibrate; NANA: N-acetylneuraminic acid. Data are expressed as the means ± SD. * p<0.05 vs BC group; ** p<0.01 vs BC group

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