Table 1 Baseline characteristics of the study population
From: The triglyceride paradox in the mortality of coronary artery disease
Characteristics | Total | Tertile 1 | Tertile 2 | Tertile 3 | p value |
|---|---|---|---|---|---|
No. of patients | n = 3061 | n = 1039 | n = 1019 | n = 1003 | |
Age, yrs | 64.41 (10.68) | 66.36 (10.21) | 64.55 (10.33) | 62.24 (11.09) | < 0.001 |
Gender, men, n (%) | 2429 (79.4) | 861 (82.9) | 790 (77.5) | 778 (77.6) | 0.003 |
Medical history | |||||
Pre-hypertension, n (%) | 1684 (55.3) | 568 (54.9) | 581 (57.2) | 535 (53.7) | 0.270 |
Pre-diabetes mellitus, n (%) | 665 (21.8) | 187 (18.1) | 259 (25.5) | 219 (22.0) | < 0.001 |
Pre-myocardial infarction, n (%) | 830 (27.1) | 303 (29.2) | 283 (27.8) | 244 (24.3) | 0.041 |
Pre-PCI, n(%) | 365 (11.9) | 143 (13.8) | 114 (11.2) | 108 (10.8) | 0.076 |
Pre-CABG, n(%) | 34 (1.1) | 9 (0.9) | 13 (1.3) | 12 (1.2) | 0.642 |
At admission | |||||
Systolic blood pressure, mm Hg | 130.72 (22.33) | 129.09 (23.12) | 131.21 (22.92) | 131.91 (20.76) | 0.013 |
Diastolic blood pressure, mm Hg | 76.49 (12.57) | 75.31 (12.76) | 76.58 (12.38) | 77.62 (12.46) | < 0.001 |
Heart rate, beats/min | 74.34 (22.98) | 74.88 (29.59) | 74.30 (22.92) | 73.82 (13.11) | 0.584 |
Killip classification ≥ II, n (%) | 345 (11.3) | 136 (13.1) | 121 (11.9) | 88 (8.8) | 0.007 |
GRACE score | 92.74 (26.00) | 96.44 (25.92) | 93.32 (25.94) | 88.30 (25.49) | < 0.001 |
BMI | 24.40 (6.75) | 23.55 (3.34) | 24.72 (10.34) | 24.94 (4.23) | < 0.001 |
Laboratory values | |||||
Serum creatinine, μmol/L | 93.90 (50.39) | 89.46 (30.49) | 96.19 (57.84) | 96.19 (58.01) | 0.002 |
Blood glucose, mmol/L | 6.95 (3.13) | 6.57 (2.75) | 7.09 (3.27) | 7.20 (3.294) | < 0.001 |
Total cholesterol, mmol/L | 4.07 (1.12) | 3.69 (0.94) | 4.02 (1.00) | 4.52 (1.25) | < 0.001 |
TG, mmol/L | 1.75 (1.13) | 0.91 (0.18) | 1.48 (0.19) | 2.89 (1.32) | < 0.001 |
LDL, mmol/L | 2.46 (3.48) | 2.14 (0.80) | 2.41 (0.89) | 2.83 (5.95) | < 0.001 |
HDL, mmol/L | 1.15 (0.35) | 1.26 (0.34) | 1.15 (0.36) | 1.03 (0.31) | < 0.001 |
Hemoglobin, g/L | 134.39 (31.12) | 131.54 (16.76) | 133.48 (18.05) | 138.28 (48.10) | < 0.001 |
White blood cell, n×109/L | 7.48 (4.94) | 7.13 (3.00) | 7.69 (7.06) | 7.64 (3.78) | 0.017 |
Severity of CAD | |||||
Left main artery, n (%) | 284 (9.3) | 95 (9.1) | 102 (10.0) | 87 (8.7) | 0.575 |
Three vessel diseases, n (%) | 795 (26.0) | 246 (23.7) | 280 (27.5) | 269 (26.8) | 0.109 |
No. of stents | 1.22 (1.22) | 1.17 (1.19) | 1.26 (1.21) | 1.24 (1.27) | 0.195 |
Diagnose | |||||
ACS, n(%) | 2174 (71.0) | 715 (68.8) | 715 (70.2) | 744 (74.2) | 0.022 |
AMI, n(%) | 636 (20.8) | 219 (21.1) | 213 (20.9) | 204 (20.3) | 0.912 |
Discharge medications | |||||
Aspirin, n (%) | 2812 (91.9) | 951 (91.5) | 938 (92.1) | 923 (92.0) | 0.963 |
Clopidogrel, n (%) | 2735 (89.3) | 905 (87.1) | 917 (90.0) | 913 (91.0) | 0.088 |
Statins, n (%) | 2754 (90.0) | 934 (89.9) | 921 (90.4) | 899 (89.6) | 0.958 |
ACE inhibitors or ARBs, n (%) | 1753 (57.3) | 601 (57.8) | 572 (56.1) | 580 (57.8) | 0.950 |
Beta-receptor blockers, n (%) | 2028 (66.3) | 634 (61.0) | 671 (65.8) | 723 (72.1) | < 0.001 |