Association between serum/plasma levels of adiponectin and obstructive sleep apnea hypopnea syndrome: a meta-analysis

Table 3 Subgroup analysis of adiponectin levels in osa patients and controls

Subgroup	N	SMD (95%CI)	z	p	Test of heterogeneity
					I²	p
Overall	28	−0.71 (− 0.92, − 0.49)	6.52	< 0.001	73%	< 0.001
Race
White	17	−0.42 (− 0.64, − 0.21)	3.87	< 0.001	56%	0.003
Nonwhite	11	−1.11 (−1.40, −0.82)	7.48	< 0.01	64%	0.002
Assay approaches
ELISA	19	−0.72 (−0.94, − 0.50)	6.37	< 0.001	65%	< 0.001
RIA	9	−0.67 (−1.17, − 0.17)	2.63	0.009	84%	< 0.001
Adiponectin Source
Serum	19	−0.89 (−1.13, − 0.65)	7.16	< 0.001	66%	< 0.001
Plasma	9	−0.36 (− 0.67, − 0.04)	2.20	0.03	71%	< 0.001
BMI
BMI ≥ 30	12	−0.46 (−0.68, − 0.23)	3.89	< 0.001	49%	0.03
BMI < 30	15	−0.85 (−1.16, − 0.53)	5.25	< 0.001	76%	< 0.001
Age
Age ≥ 50	13	−0.85 (−1.18, − 0.53)	5.15	< 0.001	74%	< 0.001
Age < 50	15	−0.58 (− 0.84, − 0.31)	4.25	< 0.001	69%	< 0.001
AHI
AHI ≥ 30	17	−0.69 (−1.00, − 0.37)	4.29	< 0.001	80%	< 0.001
AHI < 30	10	−0.70 (− 0.97, − 0.43)	5.03	< 0.001	58%	0.01

ISSN: 1476-511X