Fig. 2From: Total cholesterol to high-density lipoprotein cholesterol ratio is a significant predictor of nonalcoholic fatty liver: Jinchang cohort studyDose-response relationship of TC, HDL-C, TC/HDL-C and the risk of NAFLD. By using RCS analysis, Cox regression model was applied to evaluate the Hazard Ratio (HR) of NAFLD. After adjusting sex, age, profession and education these possible confounding factors (See details in Additional file 1: Table S1), the HR of NAFLD had non-linearity positive relationship with TC/HDL-C (Poverall<0.0001, Pnon-linearity<0.0001) and TC (Poverall<0.0001, Pnon-linearity = 0.0069), non-linearity negative relationship with HDL-C (Poverall<0.0001, Pnon-linearity<0.0001). HR, Hazards Ratio; TC, Total cholesterol; HDL-C, High-density lipoprotein cholesterol; TC/HDL-C, Total cholesterol/ High-density lipoprotein cholesterolBack to article page