Table 2 Distribution of genotypes and allele frequencies of I148M and E167K variants in the whole subjects
Controls n (%) | NAFLD n (%) | χ 2 | P value | |
|---|---|---|---|---|
PNPLA3 I148M | ||||
CC | 196 (43.46) | 114 (22.27) | ||
CG | 194 (43.02) | 236 (46.09) | ||
GG | 61 (13.52) | 162 (31.64) | 67.946 | 0.000 |
Allele C | 586 (64.97) | 464 (45.31) | ||
Allele G | 316 (35.03) | 560 (54.69) | 74.711 | 0.000 |
TM6SF2 E167K | ||||
CC | 415 (92.02) | 426 (83.20) | ||
CT | 35 (7.76) | 80 (15.63) | ||
TT | 1 (0.22) | 6 (1.17) | 17.530 | 0.000 |
Allele C | 865 (95.90) | 932 (91.02) | ||
Allele T | 37 (4.10) | 92 (8.98) | 18.293 | 0.000 |