PNPLA3 I148M | TM6SF2 E167K | |||||||
---|---|---|---|---|---|---|---|---|
Noncarriers | Carriers | t | P value | Noncarriers | Carriers | t | P value | |
N | 310 | 653 | 841 | 122 | ||||
BMI(kg/m^2) | 24.17 ± 3.41 | 25.00 ± 3.70 | −3.323 | 0.000 | 24.73 ± 3.64 | 24.75 ± 3.55 | −0.053 | 0.958 |
ALB(g/L) | 46.59 ± 2.22 | 46.47 ± 2.78 | 0.629 | 0.529 | 46.47 ± 2.38 | 46.82 ± 3.86 | −0.997 | 0.321 |
FPG (mmol/L) | 4.75 ± 1.21 | 4.90 ± 2.34 | −1.064 | 0.288 | 4.87 ± 2.16 | 4.75 ± 1.02 | −0.556 | 0.578 |
ALT (U/L) | 23.68 ± 18.04 | 31.64 ± 23.02 | −5.837 | 0.000 | 28.91 ± 22.31 | 30.25 ± 18.44 | −0.634 | 0.527 |
AST (U/L) | 21.86 ± 7.06 | 24.82 ± 11.81 | −4.851 | 0.000 | 23.73 ± 10.57 | 24.83 ± 10.77 | −1.070 | 0.285 |
GGT (U/L) | 30.83 ± 25.99 | 38.77 ± 34.60 | −3.960 | 0.000 | 36.68 ± 33.02 | 32.98 ± 26.55 | 1.185 | 0.236 |
ALP (U/L) | 64.86 ± 15.67 | 72.53 ± 25.52 | −5.731 | 0.000 | 69.72 ± 22.87 | 72.40 ± 24.54 | −1.195 | 0.232 |
TG (mmol/L) | 1.27 ± 0.81 | 1.92 ± 1.66 | −8.124 | 0.000 | 1.75 ± 1.52 | 1.43 ± 0.99 | 3.057 | 0.003 |
TC (mmol/L) | 5.25 ± 0.99 | 5.39 ± 1.04 | −2.000 | 0.046 | 5.38 ± 1.05 | 5.15 ± 0.80 | 2.788 | 0.006 |
HDL (mmol/L) | 1.33 ± 0.25 | 1.33 ± 0.28 | 0.042 | 0.967 | 1.32 ± 0.27 | 1.38 ± 0.33 | −1.863 | 0.065 |
LDL (mmol/L) | 3.03 ± 0.76 | 3.48 ± 1.20 | −6.723 | 0.000 | 3.35 ± 1.12 | 3.23 ± 0.91 | 1.125 | 0.261 |
UA (mmol/L) | 342.72 ± 94.88 | 365.84 ± 92.41 | −3.581 | 0.000 | 359.04 ± 95.72 | 354.13 ± 79.58 | 0.619 | 0.536 |