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Table 1 Baseline characteristics of participants

From: Estimated glomerular filtration rate and arterial stiffness in Japanese population: a secondary analysis based on a cross-sectional study

eGFR (quartile)

Q1 (39.00–61.82)

Q2 (62.00–69.00)

Q3 (69.29–78.00)

Q4 (78.00–122.28)

P-value

P-value*

N (cases)

225

224

235

228

  

Age mean (std), year

55.42 (8.58)

53.19 (8.04)

49.79 (9.94)

46.26 (9.05)

< 0.001

< 0.001

BMI mean (std), kg/m2

23.54 (2.79)

23.15 (2.83)

23.04 (3.01)

22.79 (3.74)

0.028

0.008

SBp mean (std), mmHg

122.60 (13.95)

120.73 (14.83)

121.00 (15.19)

116.67 (15.28)

< 0.001

< 0.001

DBp mean (std), mmHg

78.15 (9.61)

76.24 (9.97)

76.64 (10.34)

73.55 (9.62)

< 0.001

< 0.001

AST mean (std), U/L

21.45 (7.61)

21.05 (8.00)

20.86 (7.89)

20.06 (8.79)

0.316

0.115

ALT mean (std), U/L

23.33 (13.17)

22.48 (14.19)

22.89 (13.70)

22.04 (16.02)

0.799

0.374

Log2GGT mean (std) IU/L

4.47 (0.87)

4.34 (0.87)

4.39 (0.78)

4.23 (0.85)

0.026

0.003

FBS mean (std), mg/dl

101.70 (20.82)

97.91 (11.90)

97.07 (10.12)

95.60 (10.05)

< 0.001

< 0.001

Uric acid mean (std), mg/dl

5.85 (1.46)

5.21 (1.23)

5.24 (1.21)

4.72 (1.36)

< 0.001

< 0.001

TC mean (std), mg/dl

214.29 (35.46)

213.60 (33.37)

208.66 (37.60)

202.87 (36.30)

0.002

0.003

Triglycerides mean (std), mg/dL

113.17 (72.46)

96.12 (58.85)

102.71 (95.93)

87.47 (64.11)

0.003

< 0.001

HDL-C mean (std), mg/dL

51.43 (14.25)

53.32 (14.63)

53.67 (14.72)

55.68 (14.56)

0.021

0.009

LDL-C mean (std), mg/dL

132.15 (31.87)

131.84 (29.45)

126.26 (32.87)

122.16 (31.50)

0.001

0.002

ABI

1.20 (0.12)

1.25 (0.08)

1.20 (0.09)

1.18 (0.07)

0.338

0.095

baPWV mean (std), cm/s

1510.68 (307.37)

1442.92 (252.29)

1392.46 (198.00)

1319.37 (166.24)

< 0.001

< 0.001

Sex

    

< 0.001

male n(%)

164 (72.89%)

134 (59.82%)

168 (71.49%)

126 (55.26%)

  

female n(%)

61 (27.11%)

90 (40.18%)

67 (28.51%)

102 (44.74%)

  

Smoking status

    

0.132

None n(%)

185 (82.22%)

181 (80.80%)

180 (76.60%)

169 (74.12%)

  

Current n(%)

40 (17.78%)

43 (19.20%)

55 (23.40%)

59 (25.88%)

  

Ex-Smoker n%)

    

0.333

no n(%)

105 (46.67%)

121 (54.02%)

114 (48.51%)

121 (53.07%)

  

Yes n(%)

120 (53.33%)

103 (45.98%)

121 (51.49%)

107 (46.93%)

  

Alcohol consumption

    

0.007

0–40 g/week n(%)

142 (64.25%)

153 (68.61%)

125 (54.11%)

161 (71.88%)

  

40–140 g/week n(%)

32 (14.48%)

34 (15.25%)

57 (24.68%)

27 (12.05%)

  

140–280 g/week n(%)

24 (10.86%)

21 (9.42%)

25 (10.82%)

18 (8.04%)

  

> 280 g/week n(%)

23 (10.41%)

15 (6.73%)

24 (10.39%)

18 (8.04%)

  

Regular exerciser

    

0.277

no n(%)

178 (80.54%)

172 (78.54%)

180 (77.59%)

189 (84.38%)

  

yes n(%)

43 (19.46%)

47 (21.46%)

52 (22.41%)

35 (15.62%)

  

Fatty liver

    

0.138

None n(%)

145 (64.73%)

163 (72.77%)

172 (73.19%)

166 (72.81%)

  

Moderate or severe n(%)

79 (35.27%)

61 (27.23%)

63 (26.81%)

62 (27.19%)

  

Menopausal status

    

< 0.001

Postmenopausal n(%)

23 (37.70%)

19 (21.11%)

30 (44.78%)

66 (64.71%)

  

no n(%)

38 (62.30%)

71 (78.89%)

37 (55.22%)

36 (35.29%)

  
  1. Noted: P* was calculated by Kruskal-Wallis H test
  2. BMI, body mass inex; ALT, alanine aminotransferase; AST, aspartate aminotransferase;
  3. FBS, fasting blood glucose; TC, total cholesterol; HDL-C, ligh density lipoprotein;
  4. LDL-C, low-density lipoprotein; ABI, ankle brachial index; baPWV, brachial-ankle pulse wave velocity