ATP-binding cassette sub-family a member1 gene mutation improves lipid metabolic abnormalities in diabetes mellitus

Table 1 Main characteristics of the included studies in the pooled analysis

First author	Year	Ethnicity	Subjects, n cases/controls	Mean age, y cases/controls	FBG in cases/controls (mmol/l)	CHO in cases/controls (mmol/l)	TG in cases/controls (mmol/l)	HDL in cases/controls (mmol/l)	LDL in cases/controls (mmol/l)	Test for HWE X² p
Three studies for the ABCA1-C69T polymorphism
Khalid K Alharbi	2013	Caucasian	376/380	50.6 ± 10.3/46.0 ± 7.6	9.40 ± 1.5/8.69 ± 1.82	5.63 ± 1.26/5.05 ± 0.97	2.23 ± 1.65/1.61 ± 0.86	0.93 ± 0.75/0.64 ± 0.23	3.79 ± 1.07/3.68 ± 0.85	2.64
Polin Haghvirdizadeh	2015	Caucasian	164/165	62.1 ± 9.5/54.9 ± 11.7	8.66 ± 3.50/5.45 ± 1.31	4.38 ± 1.14/4.43 ± 1.17	1.76 ± 1.20/1.27 ± 0.76	1.26 ± 0.48/1.21 ± 0.43	2.35 ± 0.90/2.62 ± 0.95	21.61
H. Arzu Ergen	2012	Caucasian	107/50	NA/NA	9.85 ± 3.76/5.29 ± 1.41	5.49 ± 1.50/3.94 ± 0.71	1.96 ± 1.10/1.23 ± 0.39	0.97 ± 0.24/0.98 ± 0.36	3.67 ± 1.38/2.46 ± 0.67	0.59
Three studies for the ABCA1-R230C polymorphism
Polin Haghvirdizadeh	2015	Caucasian	173/165	62.1 ± 9.5/54.9 ± 11.7	8.66 ± 3.50/5.45 ± 1.31	4.38 ± 1.14/4.43 ± 1.17	1.76 ± 1.20/1.27 ± 0.76	1.26 ± 0.48/1.21 ± 0.43	2.35 ± 0.90/2.62 ± 0.95	4.23
Desmond D. Campbel	2012	Caucasian	800/367	63.0/54.6	NA/NA	NA/NA	NA/NA	NA/NA	NA/NA	0.01
J.C. Lara-Riegos	2015	Caucasian	126/165	51.6/42.1	10.3 ± 5.1/5.3 ± 0.61	4.7 ± 1.0/4.6 ± 0.97	2.2 (1.6–3.2)/1.8 (1.3–2.5)	1.0 ± 0.24/1.0 ± 0.29	2.8 ± 0.84/2.8 ± 0.79	21.61

FBG Fasting blood glucose, CHO Cholesterol, TG Triglyceride, HDL High density lipoprotein, LDL Low density lipoprotein, NA Not available, HWE Hardy Weinberg equilibrium

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