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Table 5 Clinical Characteristics of TRIB1 rs17321515 A Carriers and Non-Carriers in the Study Populationa

From: TRIB1 rs17321515 and rs2954029 gene polymorphisms increase the risk of non-alcoholic fatty liver disease in Chinese Han population

Characteristic

Overall Series

NAFLD Patients

Controls

Carriers

(n = 200)

Non-Carriers

(n = 104)

P Value

Carriers

(n = 102)

Non-Carriers

(n = 37)

P Value

Carriers

(n = 98)

Non-Carriers

(n = 67)

P Value

Female, %

94 (47.0)

50 (48.1)

0.858

48 (47.1)

17 (45.9)

0.907

46 (46.9)

33 (49.3)

0.770

Age, y

60.40 ± 13.96

60.82 ± 13.73

0.801

60.37 ± 15.53

62.83 ± 16.14

0.399

60.42 ± 12.18

59.76 ± 12.29

0.735

BMI, kg/m2

24.68 ± 4.29

24.12 ± 3.57

0.255

27.01 ± 4.19

26.73 ± 2.86

0.702

22.27 ± 2.81

22.66 ± 3.02

0.397

ALT, U/L

27.27 ± 22.09

23.65 ± 14.97

0.093

30.23 ± 17.19

29.25 ± 19.07

0.766

24.18 ± 25.97

19.92 ± 9.90

0.143

AST, U/L

23.74 ± 11.88

23.19 ± 11.11

0.691

24.26 ± 8.57

24.12 ± 10.14

0.937

23.21 ± 14.57

22.50 ± 11.40

0.736

GGT, U/L

36.88 ± 37.78

29.70 ± 20.29

0.032

40.72 ± 26.74

36.68 ± 25.92

0.411

32.88 ± 46.39

25.70 ± 15.16

0.156

ALP, U/L

72.94 ± 20.38

70.80 ± 23.17

0.407

71.83 ± 15.31

68.90 ± 19.77

0.344

74.09 ± 24.61

72.08 ± 24.80

0.607

TG, mmol/L

1.98 ± 1.20

1.56 ± 1.07

0.003

1.95 ± 1.34

1.83 ± 1.24

0.599

2.33 ± 0.72

1.35 ± 0.86

0.893

TC, mmol/L

5.37 ± 1.40

4.58 ± 1.29

< 0.001

5.42 ± 0.80

5.60 ± 0.88

0.254

4.09 ± 1.21

3.93 ± 1.46

0.002

HDL, mmol/L

1.25 ± 0.29

1.25 ± 0.36

0.891

1.19 ± 0.21

1.21 ± 0.22

0.654

1.31 ± 0.34

1.29 ± 0.41

0.706

LDL, mmol/L

3.28 ± 0.68

2.91 ± 0.68

< 0.001

3.44 ± 0.59

3.32 ± 0.49

0.025

3.11 ± 0.77

3.09 ± 0.59

0.863

TBIL, umol/L

12.83 ± 4.62

13.56 ± 5.18

0.209

12.79 ± 4.36

14.06 ± 5.31

0.180

12.87 ± 4.90

13.16 ± 4.98

0.708

FPG, mmol/L

5.20 ± 1.70

4.91 ± 1.12

0.107

5.75 ± 2.14

5.30 ± 1.22

0.115

4.64 ± 0.71

4.65 ± 0.95

0.887

  1. Abbreviations: BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyltransferase, ALP alkaline phosphatase, TG triglyceride, TC total cholesterol, HDL high-density lipoprotein, LDL low-density lipoprotein, TBIL total bilirubin, FPG fasting plasma glucose, NAFLD nonalcoholic fatty liver disease
  2. aValues are expressed as mean ± SD and compared by Student’s t-test