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Table 3 Associations with antidepressants presented for all 292 T1D patients and gender specifically

From: Lower HDL-cholesterol, a known marker of cardiovascular risk, was associated with depression in type 1 diabetes: a cross sectional study

Antidepressants
   All
N = 292
Men
N = 162
Women
N = 127
COR P AOR P a AOR P a AOR P a
Gender (women) 1.4 (0.6–3.3) 0.44 1.3 (0.5–3.5) 0.61
Age (per year) 1.04 (1.0–1.1) 0.068 1.01 (0.96–1.07) 0.59 1.00 (0.93–1.08) 0.89 1.03 (0.96–1.10) 0.42
Diabetes duration (per year) 1.02 (0.99–1.06) 0.19 1.04 (0.99–1.10) 0.11
Depression (HADS ≥8p) 9.6 (3.7–24.6) < 0.001 10.6 (4.0–28.6) < 0.001 10.6 (2.8–40.3) 0.001 10.8 (2.4–48.5) 0.002
High HbA1c (> 70 mmol/mol) 2.7 (1.1–6.3) 0.026 1.4 (0.5–3.8) 0.46 2.8 (0.7–11.1) 0.15
Total cholesterol (per mmol/l) 0.98 (0.6–1.5) 0.92
Triglycerides (per mmol/l) 1.1 (0.7–1.8) 0.72
HDL-cholesterol (per mmol/l) 0.8 (0.3–2.7) 0.76
LDL-cholesterol (per mmol/l) 0.9 (0.5–1.6) 0.81
Hs-CRP e (per mg/l) 1.1 (0.8–1.5) 0.42
Abdominal obesity b 2.9 (1.2–7.2) 0.024 2.7 (1.0–7.4) 0.052 4.6 (1.2–18.3) 0.029
BMI (kg/m2) (4 weight classes) 0.56
SBP (per mm Hg) 1.00 (0.96–1.03) 0.81
DBP (per mm Hg) 1.05 (0.99–1.11) 0.087 1.05 (0.98–1.12) 0.14 1.08 (0.99–1.18) 0.092
Hypoglycemia > 0.99
Smoking c 0.4 (0.05–3.1) 0.38
Physical inactivity (< 0.5 h/week) 1.8 (0.6–5.5) 0.34
Physical activity (4 levels) 0.40
LLD 2.3 (1.0–5.7) 0.063 2.3 (0.9–5.9) 0.099
AHD 1.6 (0.7–3.8) 0.28 2.3 (0.6–9.2) 0.25
Insulin and OAD 1.6 (0.3–7.5) 0.54
  1. aMultiple logistic regression analysis (Backward: Wald). b N = 292/162/. All/men/women: N = 292/162/127; Hosmer and Lemeshow 0.370/0.787/0.54; Nagelkerke 0.210/0.160/0.274