Table 3 Associations with antidepressants presented for all 292 T1D patients and gender specifically

Gender (women)

1.4 (0.6–3.3)

0.44

1.3 (0.5–3.5)

0.61

–

–

–

–

Age (per year)

1.04 (1.0–1.1)

0.068

1.01 (0.96–1.07)

0.59

1.00 (0.93–1.08)

0.89

1.03 (0.96–1.10)

0.42

Diabetes duration (per year)

1.02 (0.99–1.06)

0.19

–

–

1.04 (0.99–1.10)

0.11

–

–

Depression (HADS ≥8p)

9.6 (3.7–24.6)

< 0.001

10.6 (4.0–28.6)

< 0.001

10.6 (2.8–40.3)

0.001

10.8 (2.4–48.5)

0.002

High HbA1c (> 70 mmol/mol)

2.7 (1.1–6.3)

0.026

1.4 (0.5–3.8)

0.46

–

–

2.8 (0.7–11.1)

0.15

Total cholesterol (per mmol/l)

0.98 (0.6–1.5)

0.92

–

–

–

–

–

–

Triglycerides (per mmol/l)

1.1 (0.7–1.8)

0.72

–

–

–

–

–

–

HDL-cholesterol (per mmol/l)

0.8 (0.3–2.7)

0.76

–

–

–

–

–

–

LDL-cholesterol (per mmol/l)

0.9 (0.5–1.6)

0.81

–

–

–

–

–

–

Hs-CRP ^e (per mg/l)

1.1 (0.8–1.5)

0.42

–

–

–

–

–

–

Abdominal obesity ^b

2.9 (1.2–7.2)

0.024

2.7 (1.0–7.4)

0.052

–

–

4.6 (1.2–18.3)

0.029

BMI (kg/m²) (4 weight classes)

–

0.56

–

–

–

–

–

–

SBP (per mm Hg)

1.00 (0.96–1.03)

0.81

–

–

–

–

–

–

DBP (per mm Hg)

1.05 (0.99–1.11)

0.087

1.05 (0.98–1.12)

0.14

–

–

1.08 (0.99–1.18)

0.092

Hypoglycemia

–

> 0.99

–

–

–

–

–

–

Smoking ^c

0.4 (0.05–3.1)

0.38

–

–

–

–

–

–

Physical inactivity (< 0.5 h/week)

1.8 (0.6–5.5)

0.34

–

–

–

–

–

–

Physical activity (4 levels)

–

0.40

–

–

–

–

–

–

LLD

2.3 (1.0–5.7)

0.063

2.3 (0.9–5.9)

0.099

–

–

–

–

AHD

1.6 (0.7–3.8)

0.28

–

–

–

–

2.3 (0.6–9.2)

0.25

Insulin and OAD

1.6 (0.3–7.5)

0.54

–

–

–

–

–

–