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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: High olive oil diets enhance cervical tumour growth in mice: transcriptome analysis for potential candidate genes and pathways

Fig. 1

High olive oil diet feeding promotes the growth of xenografts in nude mice. HeLa cells were injected subcutaneously into 4-week-old nude mice fed a control or an olive oil diet ad libitum. At 6 weeks after implantation, the animals were sacrificed, and the tumour masses were excised. a Representative graph of tumours formed by the implantation of HeLa cells under different diets. b Analysis of tumour growth curves over a 6-week time course. c Tumour weights in different diet groups of nude mice. d Top, H&E-stained sections of xenografts. Bottom, Immunohistochemical staining of tumour sectios using an anti-PCNA antibody. Original magnification, × 400. Right, quantification of the percentage of the PCNA-positive area. The data were statistically analysed using Student’s t-test, and values are shown as the means ± SD. *P < 0.05, ***P < 0.001

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Lipids in Health and Disease

ISSN: 1476-511X