The severity of rat liver injury by fructose and high fat depends on the degree of respiratory dysfunction and oxidative stress induced in mitochondria

Table 1 Experimental groups and preparation of diets

Diet components	Experimental groups
Diet components	Control	HF	Fr	HF + Fr
Standard rodent chow^b, %	100	47.5	100	47.5
Lard^c, %		10.1		10.1
Hydrogenated vegetable oil^d, %		40.6		40.6
Sodium cholate^e, %		1.3		1.3
Choline chloride^e, %		0.3		0.3
Thiouracil^e, %		0.2		0.2
Fructose^f, %w/v			25^a	25^a

Diets were provided during 6 weeks to Wistar rats with an initial weight of 250-350 g. ^aFructose was given in the drinking water. ^bLaboratory Rodent Diet 5001, LabDiet, St. Louis, MO, USA. The composition of this diet can be consulted in [49]. ^cJC Fortes, Empacadora San Benito, México. ^dManteca Inca, ACH Foods México, S. de R.L. de C.V. ^eSigma-Aldrich, St. Louis, MO, USA. ^fGrupo Químico Contreras, S.A. de C.V. México

ISSN: 1476-511X