Table 5 GO classification of target genes
From: Screening of differentially expressed microRNAs of essential hypertension in Uyghur population
Enrichment Score | Term | Count | % | P-value |
|---|---|---|---|---|
5.55 | GO:0000267~cell fraction | 117 | 8.93 | 2.35E-06 |
GO:0005624~membrane fraction | 93 | 7.10 | 2.56E-06 | |
GO:0005626~insoluble fraction | 95 | 7.25 | 3.76E-06 | |
4.90 | GO:0030424~axon | 31 | 2.37 | 6.00E-07 |
GO:0043005~neuron projection | 49 | 3.74 | 3.38E-06 | |
GO:0042995~cell projection | 72 | 5.50 | 9.96E-04 | |
4.33 | GO:0007156~homophilic cell adhesion | 32 | 2.44 | 3.32E-09 |
GO:0016337~cell-cell adhesion | 40 | 3.05 | 5.08E-05 | |
cell adhesion | 50 | 3.82 | 1.66E-04 | |
GO:0007155~cell adhesion | 72 | 5.50 | 0.002747 | |
GO:0022610~biological adhesion | 72 | 5.50 | 0.002857 | |
3.46 | GO:0046872~metal ion binding | 367 | 28.02 | 1.88E-05 |
zinc-finger | 160 | 12.21 | 2.68E-05 | |
GO:0043169~cation binding | 367 | 28.02 | 4.67E-05 | |
GO:0043167~ion binding | 370 | 28.24 | 7.72E-05 | |
zinc | 188 | 14.35 | 4.53E-04 | |
metal-binding | 243 | 18.55 | 9.94E-04 | |
3.44 | transcription regulation | 195 | 14.89 | 3.24E-07 |
Transcription | 198 | 15.11 | 3.92E-07 | |
nucleus | 364 | 27.79 | 7.14E-07 | |
GO:0030528~transcription regulator activity | 152 | 11.60 | 6.06E-05 | |
GO:0045449~regulation of transcription | 234 | 17.86 | 2.32E-04 | |
GO:0006350~transcription | 191 | 14.58 | 6.37E-04 | |
GO:0043565~sequence-specific DNA binding | 65 | 4.96 | 0.002591 | |
GO:0003700~transcription factor activity | 95 | 7.25 | 0.004676 | |
3.22 | GO:0014069~postsynaptic density | 18 | 1.37 | 6.30E-06 |
GO:0045202~synapse | 48 | 3.66 | 2.05E-05 | |
GO:0030054~cell junction | 61 | 4.66 | 9.09E-05 | |
cell junction | 47 | 3.59 | 3.04E-04 | |
synapse | 29 | 2.21 | 5.96E-04 | |
GO:0044456~synapse part | 29 | 2.21 | 0.00823 | |
3.20 | ubl conjugation pathway | 62 | 4.73 | 1.05E-05 |
GO:0051603~proteolysis involved in cellular protein catabolic process | 70 | 5.34 | 1.00E-04 | |
GO:0044257~cellular protein catabolic process | 70 | 5.34 | 1.15E-04 | |
GO:0043632~modification-dependent macromolecule catabolic process | 66 | 5.04 | 2.46E-04 | |
GO:0019941~modification-dependent protein catabolic process | 66 | 5.04 | 2.46E-04 | |
GO:0030163~protein catabolic process | 70 | 5.34 | 2.89E-04 | |
GO:0006511~ubiquitin-dependent protein catabolic process | 34 | 2.60 | 3.62E-04 | |
GO:0044265~cellular macromolecule catabolic process | 74 | 5.65 | 0.002887 | |
3.12 | kinase | 80 | 6.11 | 2.92E-06 |
nucleotide-binding | 159 | 12.14 | 1.50E-05 | |
transferase | 132 | 10.08 | 7.49E-05 | |
atp-binding | 125 | 9.54 | 1.39E-04 | |
GO:0006796~phosphate metabolic process | 102 | 7.79 | 1.62E-04 | |
GO:0006793~phosphorus metabolic process | 102 | 7.79 | 1.62E-04 | |
GO:0006468~protein amino acid phosphorylation | 73 | 5.57 | 4.73E-04 | |
GO:0017076~purine nucleotide binding | 178 | 13.59 | 8.59E-04 | |
GO:0016310~phosphorylation | 83 | 6.34 | 9.76E-04 | |
GO:0032553~ribonucleotide binding | 170 | 12.98 | 0.001314 | |
GO:0032555~purine ribonucleotide binding | 170 | 12.98 | 0.001314 | |
serine/threonine-protein kinase | 43 | 3.28 | 0.001333 | |
GO:0001883~purine nucleoside binding | 148 | 11.30 | 0.003017 | |
GO:0030554~adenyl nucleotide binding | 146 | 11.15 | 0.003068 | |
GO:0000166~nucleotide binding | 199 | 15.19 | 0.0037 | |
GO:0001882~nucleoside binding | 148 | 11.30 | 0.003985 | |
GO:0005524~ATP binding | 137 | 10.46 | 0.004062 | |
GO:0032559~adenyl ribonucleotide binding | 138 | 10.53 | 0.004694 |