Association between lipoproteins and telomere length in US adults: data from the NHANES 1999–2002

Table 3 Results of standard linear regression model and two-piecewise linear regression model

Outcome:	LDL-cholesterol β (95% CI)	Triglycerides β (95% CI)	HDL-Cholesterol β (95% CI)
Fitting model by standard linear regression	0.21 (− 0.30, 0.72)	−1.42 (−2.75, − 0.09)	0.17 (0.04, 0.31)
Fitting model by two-piecewise linear regression
Inflection point of telomere length (per 0.1 change)	7.33	7.21	12.52
≤ inflection point	3.11 (−2.21, 8.43)	7.07 (− 9.03, 23.17)	0.50 (0.27, 0.73)
> inflection point	0.22 (−0.32, 0.76)	−1.77 (− 3.21, − 0.32)	−0.22 (− 0.53, 0.09)
P for log likelihood ratio test	0.297	0.291	0.001

All results presented in Table 3 were calculated by pre-imputation data. All models adjusted the same covariates, including age (Smooth); any CAD (self report); any family with heart attack or angina; sex; poverty to income ratio(Smooth); martial status; race; education; ALT (Smooth); AST (Smooth); blood urea nirogen (Smooth); creatinine (Smooth); Uric acid (Smooth); C reaction protein (smooth); BMI (Smooth); physical activity; current or past cigarette smoker?; alcohol (Smooth); caffeine (Smooth); calcium (Smooth); carbohydrate (Smooth); cholesterol (Smooth); dietary fiber (Smooth); energy (Smooth); total monounsaturated fatty acids (Smooth); total polyunsaturated fatty acids (Smooth); total saturated fatty acids (Smooth); total fat (Smooth); any diabetes; any hypertension

ISSN: 1476-511X