From: Integrated analysis of gene expression changes associated with coronary artery disease
Parameter | Univariate HR (95% CI) | P-value | Multivariate HR (95% CI) | P-value |
---|---|---|---|---|
Age | 1.003(0.984–1.022) | 0.766 | 1.006(0.979–1.034) | 0.660 |
Sex | ||||
 Male | 1 | – | 1 | – |
 Female | 0.645(0.137–1.311) | 0.225 | 0.442(0.145–1.351) | 0.152 |
Cigarette Smoking | ||||
 No | 1 | – | 1 | – |
 Yes | 1.506(0.831–2.727) | 0.011 | 1.910(0.699–5.222) | 0.020 |
Alcohol Drinking | ||||
 No | 1 | – | 1 | – |
 Yes | 0.507(0.319–1.772) | 0.043 | 0.986(0.580–2.805) | 0.094 |
Dyslipidemia | ||||
 No | 1 | – | 1 | – |
 Yes | 1.959(1.557–2.651) | 0.023 | 1.831(1.375–2.842) | 0.064 |
Hypertension | ||||
 No | 1 | – | 1 | – |
 Yes | 1.914(1.085–3.375) | 0.025 | 1.187(0.622–2.264) | 0.060 |
Diabetes Mellitus | ||||
 No | 1 | – | 1 | – |
 Yes | 1.970(1.103–3.518) | 0.022 | 3.679(1.634–8.283) | 0.002 |
IL1B | 1.945(1.829–2.077) | 0.009 | 1.896(1.435–2.845) | 0.017 |
ICAM1 | 1.328(1.218–1.493) | 0.087 | 1.134(1.010–2.758) | 0.126 |
JUN | 1.480(1.362–1.638) | 0.059 | 1.528(1.270–5.652) | 0.083 |
CCL2 | 1.945(0.830–2.088) | 0.009 | 1.172(0.563–2.440) | 0.032 |