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Table 2 Clinical phenotypes of patients with PMI

From: Effects of familial hypercholesterolemia-associated genes on the phenotype of premature myocardial infarction

 

Patients with PMI (n = 225)

Non-PMI patients (n = 56)

P value

Male, n(%)

188 (83.6)

45 (80.4)

0.569

BMI (kg/m2)

26.71 ± 3.51

24.58 ± 4.12

0.001

Age of MI onset (years)

46.64 ± 7.21

73.73 ± 6.97

< 0.001

Family history of PCHD, n (%)

49 (21.8)

5 (8.9)

0.029

eGFR (ml/min/1.73m2)

96.72 (82.49, 104.27)

78.45 (67.71, 89.32)

< 0.001

LDL-C (mmol/L)

3.63 (2.97, 4.35)

3.29 (2.49, 3.86)

0.005

LVEF (%)

60.93 ± 10.25

60.67 ± 8.75

0.861

Gensini score

54 (34, 79)

58.5 (45.5, 83.5)

0.107

Multivessel lesion, n(%)

176 (78.2)

48 (85.7)

0.212

Smoking, n (%)

153 (68.0)

27 (48.2)

0.006

Hyperlipemia, n (%)

75 (33.3)

15 (26.8)

0.347

Hypertension, n (%)

116 (51.6)

35 (62.5)

0.142

Diabetes, n (%)

83 (36.9)

14 (25.0)

0.094

  1. PMI premature myocardial infarction, BMI body mass index, PCHD premature coronary heart disease, eGFR estimated glomerular filtration rate, LDL-C low-density lipoprotein cholesterol, LVEF left ventricular ejection fraction; All P values represented the comparisons between PMI patients and non-PMI patients. Comparisons between groups were performed with the student’s t-test for continuous variables and Chi-square test for categorical variables. P < 0.05 was considered statistically significant
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Lipids in Health and Disease

ISSN: 1476-511X