Variables | Placebo | PS | Omega-3 | PS + Omega-3 | Main effect of PS | P value | Main effect of Omega-3 | P value | Interaction | P value | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Post | Difference | Post | Difference | Post | Difference | Post | Difference | |||||||
Weight (kg) | 68.97 ± 10.89 | −0.85 ± 3.62 | 68.24 ± 8.14 | −1.28 ± 9.14 | 68.13 ± 11.17 | − 1.41 ± 1.91 | 67.35 ± 10.34 | −2.26 ± 2.81 | − 0.64 | 0.47 | −0.77 | 0.38 | −0.21 | 0.81 |
BMI (kg/m2) | 26.13 ± 3.8 | −0.33 ± 1.33 | 25.74 ± 4.24 | −0.45 ± 3.43 | 25.19 ± 2.89 | −0.50 ± 0.71 | 25.59 ± 3.55 | −0.84 ± 1.02 | − 0.23 | 0.47 | − 0.28 | 0.39 | − 0.11 | 0.73 |
Waistline (cm) | 93.96 ± 9.99 | −0.88 ± 5.84 | 90.77 ± 9.30 | 0.67 ± 6.04 | 88.50 ± 9.22 | −1.90 ± 3.86 | 88.88 ± 10.32 | −1.97 ± 4.21 | 0.74 | 0.40 | −1.83 | 0.04* | −0.81 | 0.35 |
Systolic pressure (mmHg) | 130.57 ± 13.22 | −1.79 ± 14.71 | 140.23 ± 18.33 | 2.80 ± 20.50 | 135.49 ± 12.87 | −1.20 ± 16.82 | 139.44 ± 20.99 | 0.68 ± 20.85 | 3.235 | 0.32 | − 0.77 | 0.81 | −1.36 | 0.68 |
Diastolic pressure (mmHg) | 82.5 ± 12.08 | −1.57 ± 7.52 | 82.33 ± 9.44 | −3.3 ± 14.66 | 79.94 ± 8.86 | −5.97 ± 8.23 | 81.54 ± 10.87 | −3.1 ± 8.76 | 0.57 | 0.75 | −2.10 | 0.23 | 2.30 | 0.19 |
FPG (mmol/l) | 6.43 ± 0.86 | −0.06 ± 0.8 | 6.92 ± 1.01 | 0.47 ± 0.96 | 6.34 ± 1.06 | −0.21 ± 1.19 | 5.56 ± 0.62 | −0.94 ± 0.66 | −0.1 | 0.55 | −0.78 | 0.01** | −0.63 | 0.01** |
FINS (mU/L) | 10.25 ± 3.9 | −0.02 ± 3.67 | 9.57 ± 2.96 | −0.58 ± 4.46 | 9.45 ± 3.87 | −0.40 ± 2.25 | 8.12 ± 3.45 | −2.09 ± 2.95 | −1.125 | 0.06 | −0.95 | 0.11 | −0.57 | 0.33 |
HOMA-IR | 2.93 ± 1.17 | −0.03 ± 1.04 | 2.96 ± 1.18 | 0.06 ± 1.45 | 2.72 ± 1.34 | −0.14 ± 0.70 | 2.00 ± 0.89 | −0.96 ± 0.98 | −0.365 | 0.05* | −0.57 | 0.00** | −0.46 | 0.01** |
HbA1c (%) | 6.35 ± 0.68 | −0.15 ± 0.42 | 6.34 ± 0.92 | 0.13 ± 1.11 | 6.15 ± 0.78 | −0.14 ± 0.55 | 6.01 ± 0.73 | −0.35 ± 0.51 | 0.035 | 0.78 | −0.24 | 0.05* | −0.25 | 0.05* |
TC (mmol/l) | 5.23 ± 0.89 | −1.73 ± 2.07 | 5.61 ± 0.95 | 0.18 ± 1.35 | 5.05 ± 0.70 | −0.33 ± 0.48 | 4.96 ± 1.16 | −0.39 ± 0.87 | 0.925 | 0.24 | 0.42 | 0.06 | −0.99 | 0.06 |
TG (mmol/l) | 1.82 ± 0.6 | −0.23 ± 0.46 | 1.96 ± 1.27 | −0.11 ± 1.32 | 1.95 ± 0.81 | 0.16 ± 0.95 | 1.73 ± 0.64 | −0.34 ± 0.77 | −0.19 | 0.01** | 0.08 | 0.61 | −0.31 | 0.01** |
HDL-C (mmol/l) | 1.10 ± 0.22 | −0.12 ± 0.12 | 1.16 ± 0.19 | 0.01 ± 0.30 | 1.21 ± 0.18 | 0.02 ± 0.19 | 1.27 ± 0.29 | −0.1 ± 0.31 | 0.005 | 0.90 | 0.02 | 0.73 | −0.13 | 0.05* |
LDL-C (mmol/l) | 3.02 ± 0.77 | −0.09 ± 0.45 | 2.79 ± 0.78 | 0.22 ± 1.34 | 2.92 ± 0.55 | −0.08 ± 0.78 | 2.83 ± 0.88 | −0.14 ± 0.75 | 0.125 | 0.42 | −0.18 | 0.25 | −0.19 | 0.22 |
Hs-CRP (mg/L) | 1.88 ± 0.53 | 0.4 ± 0.89 | 1.08 ± 0.46 | −0.05 ± 0.39 | 0.95 ± 0.43 | −0.15 ± 0.59 | 0.93 ± 0.38 | −0.18 ± 0.59 | −0.24 | 0.03* | −0.34 | 0.03* | 0.21 | 0.06 |
IL-6 (pg/ml) | 3.05 ± 0.87 | 0.02 ± 1.61 | 2.49 ± 1.41 | −0.33 ± 1.36 | 2.53 ± 1.37 | −0.45 ± 1.7 | 2.45 ± 1.38 | −0.4 ± 1.76 | −0.15 | 0.59 | −0.27 | 0.35 | 0.20 | 0.48 |
Body fat rate (%) | 32.28 ± 8.84 | −0.39 ± 3.9 | 28.43 ± 7.13 | −0.83 ± 4.74 | 27.68 ± 5.82 | −1.12 ± 4.75 | 28.11 ± 8.40 | −1.76 ± 2.34 | −0.54 | 0.44 | −0.83 | 0.23 | −0.1 | 0.89 |
Visceral fat rating | 11.86 ± 4.49 | −0.21 ± 1.55 | 11.03 ± 4.17 | −0.43 ± 3.62 | 11.14 ± 4.38 | −0.83 ± 1.25 | 11.27 ± 4.49 | −0.8 ± 1.47 | −0.095 | 0.79 | −0.495 | 0.19 | 0.125 | 0.74 |