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Table 1 Comparative result of biochemical indicators at different modeling time (mean ± SD, n = 8 rats)

From: Lipidomics coupled with pathway analysis characterizes serum metabolic changes in response to potassium oxonate induced hyperuricemic rats

 

Group

7 day

14 day

21 day

28 day

SUA (umol•L-1)

Control

106.41 ± 40.38

71.96 ± 21.87

81.90 ± 26.23

63.50 ± 31.06

Model

400.00 ± 169.00**

179.89 ± 33.52**

192.38 ± 96.21**

125.13 ± 18.93*

TG (mmol•L− 1)

Control

0.62 ± 0.40

0.59 ± 0.09

0.6 ± 0.15

1.09 ± 0.72

Model

0.42 ± 0.14

0.65 ± 0.24

0.51 ± 0.15

1.5 ± 0.31

CRE (umol•L− 1)

Control

31.75 ± 17.94

37.47 ± 6.11

51.73 ± 20.49

33.55 ± 17.22

Model

55.45 ± 53.84

41.04 ± 11.74

35.23 ± 3.11

35.23 ± 30.22

TP (g•L− 1)

Control

42.68 ± 5.42

41.08 ± 2.65

46.88 ± 3.84

44.78 ± 3.61

Model

46.19 ± 5.03

42.34 ± 6.67

49.86 ± 4.58

45.34 ± 4.38

  1. *P < 0.05. **P < 0.01, Compared with control group. SUA Serum uric acid, TG Triglyceride, TP Total protein, CRE Creatinine