TY - JOUR AU - Kobayashi, J. AU - Miyashita, K. AU - Nakajima, K. AU - Mabuchi, H. PY - 2015 DA - 2015// TI - Hepatic lipase: a comprehensive view of its role on plasma lipid and lipoprotein metabolism JO - J Atheroscler Thromb VL - 22 UR - https://doi.org/10.5551/jat.31617 DO - 10.5551/jat.31617 ID - Kobayashi2015 ER - TY - JOUR AU - Annema, W. AU - Tietge, U. J. PY - 2011 DA - 2011// TI - Role of hepatic lipase and endothelial lipase in high-density lipoprotein-mediated reverse cholesterol transport JO - Curr Atheroscler Rep VL - 13 UR - https://doi.org/10.1007/s11883-011-0175-2 DO - 10.1007/s11883-011-0175-2 ID - Annema2011 ER - TY - JOUR AU - Cohen, J. C. AU - Vega, G. L. AU - Grundy, S. M. PY - 1999 DA - 1999// TI - Hepatic lipase: new insights from genetic and metabolic studies JO - Curr Opin Lipidol VL - 10 UR - https://doi.org/10.1097/00041433-199906000-00008 DO - 10.1097/00041433-199906000-00008 ID - Cohen1999 ER - TY - JOUR AU - Thuren, T. PY - 2000 DA - 2000// TI - Hepatic lipase and HDL metabolism JO - Curr Opin Lipidol VL - 11 UR - https://doi.org/10.1097/00041433-200006000-00008 DO - 10.1097/00041433-200006000-00008 ID - Thuren2000 ER - TY - JOUR AU - Aulchenko, Y. S. AU - Ripatti, S. AU - Lindqvist, I. AU - Boomsma, D. AU - Heid, I. M. AU - Pramstaller, P. P. PY - 2009 DA - 2009// TI - Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts JO - Nat Genet VL - 41 UR - https://doi.org/10.1038/ng.269 DO - 10.1038/ng.269 ID - Aulchenko2009 ER - TY - JOUR AU - Chasman, D. I. AU - Pare, G. AU - Mora, S. AU - Hopewell, J. C. AU - Peloso, G. AU - Clarke, R. PY - 2009 DA - 2009// TI - Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000730 DO - 10.1371/journal.pgen.1000730 ID - Chasman2009 ER - TY - JOUR AU - Lu, X. AU - Huang, J. AU - Mo, Z. AU - He, J. AU - Wang, L. AU - Yang, X. PY - 2016 DA - 2016// TI - Genetic susceptibility to lipid levels and lipid change over time and risk of incident hyperlipidemia in Chinese populations JO - Circ Cardiovasc Genet VL - 9 UR - https://doi.org/10.1161/CIRCGENETICS.115.001096 DO - 10.1161/CIRCGENETICS.115.001096 ID - Lu2016 ER - TY - JOUR AU - Ko, Y. L. AU - Hsu, L. A. AU - Hsu, K. H. AU - Ko, Y. H. AU - Lee, Y. S. PY - 2004 DA - 2004// TI - The interactive effects of hepatic lipase gene promoter polymorphisms with sex and obesity on high-density-lipoprotein cholesterol levels in Taiwanese-Chinese JO - Atherosclerosis VL - 172 UR - https://doi.org/10.1016/j.atherosclerosis.2003.09.013 DO - 10.1016/j.atherosclerosis.2003.09.013 ID - Ko2004 ER - TY - JOUR AU - Yamazaki, K. AU - Bujo, H. AU - Taira, K. AU - Itou, N. AU - Shibasaki, M. AU - Takahashi, K. PY - 2004 DA - 2004// TI - Increased circulating malondialdehyde-modified LDL in the patients with familial combined hyperlipidemia and its relation with the hepatic lipase activity JO - Atherosclerosis VL - 172 UR - https://doi.org/10.1016/j.atherosclerosis.2003.05.001 DO - 10.1016/j.atherosclerosis.2003.05.001 ID - Yamazaki2004 ER - TY - JOUR AU - Zhang, C. AU - Lopez-Ridaura, R. AU - Rimm, E. B. AU - Li, T. AU - Hunter, D. J. AU - Hu, F. B. PY - 2006 DA - 2006// TI - Genetic variation in the hepatic lipase gene and the risk of coronary heart disease among US diabetic men: potential interaction with obesity JO - Diabetologia VL - 49 UR - https://doi.org/10.1007/s00125-006-0235-2 DO - 10.1007/s00125-006-0235-2 ID - Zhang2006 ER - TY - JOUR AU - Shohet, R. V. AU - Vega, G. L. AU - Bersot, T. P. AU - Mahley, R. W. AU - Grundy, S. M. AU - Guerra, R. PY - 2002 DA - 2002// TI - Sources of variability in genetic association studies: insights from the analysis of hepatic lipase (LIPC) JO - Hum Mutat VL - 19 UR - https://doi.org/10.1002/humu.10079 DO - 10.1002/humu.10079 ID - Shohet2002 ER - TY - JOUR AU - Hall, M. A. AU - Verma, A. AU - Brown-Gentry, K. D. AU - Goodloe, R. AU - Boston, J. AU - Wilson, S. PY - 2014 DA - 2014// TI - Detection of pleiotropy through a phenome-wide association study (PheWAS) of epidemiologic data as part of the environmental architecture for genes linked to environment (EAGLE) study JO - PLoS Genet VL - 10 UR - https://doi.org/10.1371/journal.pgen.1004678 DO - 10.1371/journal.pgen.1004678 ID - Hall2014 ER - TY - JOUR AU - Isaacs, A. AU - Sayed-Tabatabaei, F. A. AU - Njajou, O. T. AU - Witteman, J. C. AU - Duijn, C. M. PY - 2004 DA - 2004// TI - The −514 C->T hepatic lipase promoter region polymorphism and plasma lipids: a meta-analysis JO - J Clin Endocrinol Metab VL - 89 UR - https://doi.org/10.1210/jc.2004-0188 DO - 10.1210/jc.2004-0188 ID - Isaacs2004 ER - TY - JOUR AU - Ma, L. AU - Brautbar, A. AU - Boerwinkle, E. AU - Sing, C. F. AU - Clark, A. G. AU - Keinan, A. PY - 2012 DA - 2012// TI - Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations JO - PLoS Genet VL - 8 UR - https://doi.org/10.1371/journal.pgen.1002714 DO - 10.1371/journal.pgen.1002714 ID - Ma2012 ER - TY - JOUR AU - Jialal, I. AU - Vega, G. L. AU - Grundy, S. M. PY - 1990 DA - 1990// TI - Physiologic levels of ascorbate inhibit the oxidative modification of low density lipoprotein JO - Atherosclerosis VL - 82 UR - https://doi.org/10.1016/0021-9150(90)90039-L DO - 10.1016/0021-9150(90)90039-L ID - Jialal1990 ER - TY - JOUR AU - Brown, J. D. AU - Oligino, E. AU - Rader, D. J. AU - Saghatelian, A. AU - Plutzky, J. PY - 2011 DA - 2011// TI - VLDL hydrolysis by hepatic lipase regulates PPARdelta transcriptional responses JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0021209 DO - 10.1371/journal.pone.0021209 ID - Brown2011 ER - TY - STD TI - Tesse A, Andriantsitohaina R, Ragot T. PPARdelta activity in cardiovascular diseases: a potential pharmacological target. PPAR Res. 2009:745821. ID - ref17 ER - TY - JOUR AU - Lee, H. AU - Ham, S. A. AU - Kim, M. Y. AU - Kim, J. H. AU - Paek, K. S. AU - Kang, E. S. PY - 2012 DA - 2012// TI - Activation of PPARdelta counteracts angiotensin II-induced ROS generation by inhibiting rac1 translocation in vascular smooth muscle cells JO - Free Radic Res VL - 46 UR - https://doi.org/10.3109/10715762.2012.687448 DO - 10.3109/10715762.2012.687448 ID - Lee2012 ER - TY - JOUR AU - Aviram, M. PY - 1993 DA - 1993// TI - Modified forms of low density lipoprotein and atherosclerosis JO - Atherosclerosis VL - 98 UR - https://doi.org/10.1016/0021-9150(93)90217-I DO - 10.1016/0021-9150(93)90217-I ID - Aviram1993 ER - TY - JOUR AU - Zambon, A. AU - Deeb, S. S. AU - Pauletto, P. AU - Crepaldi, G. AU - Brunzell, J. D. PY - 2003 DA - 2003// TI - Hepatic lipase: a marker for cardiovascular disease risk and response to therapy JO - Curr Opin Lipidol VL - 14 UR - https://doi.org/10.1097/00041433-200304000-00010 DO - 10.1097/00041433-200304000-00010 ID - Zambon2003 ER - TY - JOUR AU - Waterworth, D. M. AU - Ricketts, S. L. AU - Song, K. AU - Chen, L. AU - Zhao, J. H. AU - Ripatti, S. AU - Aulchenko, Y. S. PY - 2010 DA - 2010// TI - Genetic variants influencing circulating lipid levels and risk of coronary artery disease JO - Arterioscler Thromb Vasc Biol VL - 30 UR - https://doi.org/10.1161/ATVBAHA.109.201020 DO - 10.1161/ATVBAHA.109.201020 ID - Waterworth2010 ER - TY - JOUR AU - Cooke, M. S. AU - Evans, M. D. AU - Herbert, K. E. AU - Lunec, J. PY - 2000 DA - 2000// TI - Urinary 8-oxo-2′-deoxyguanosine-- source, significance and supplements JO - Free Radic Res VL - 32 UR - https://doi.org/10.1080/10715760000300391 DO - 10.1080/10715760000300391 ID - Cooke2000 ER - TY - JOUR AU - Calderon-Garciduenas, L. AU - Wen-Wang, L. AU - Zhang, Y. J. AU - Rodriguez-Alcaraz, A. AU - Osnaya, N. AU - Villarreal-Calderon, A. PY - 1999 DA - 1999// TI - 8-hydroxy-2′-deoxyguanosine, a major mutagenic oxidative DNA lesion, and DNA strand breaks in nasal respiratory epithelium of children exposed to urban pollution JO - Environ Health Perspect VL - 107 ID - Calderon-Garciduenas1999 ER - TY - JOUR AU - Minno, A. AU - Turnu, L. AU - Porro, B. AU - Squellerio, I. AU - Cavalca, V. AU - Tremoli, E. PY - 2016 DA - 2016// TI - 8-Hydroxy-2-Deoxyguanosine levels and cardiovascular disease: a systematic review and meta-analysis of the literature JO - Antioxid Redox Signal VL - 24 UR - https://doi.org/10.1089/ars.2015.6508 DO - 10.1089/ars.2015.6508 ID - Minno2016 ER - TY - JOUR AU - Wu, L. L. AU - Chiou, C. C. AU - Chang, P. Y. AU - Wu, J. T. PY - 2004 DA - 2004// TI - Urinary 8-OHdG: a marker of oxidative stress to DNA and a risk factor for cancer, atherosclerosis and diabetics JO - Clin Chim Acta VL - 339 UR - https://doi.org/10.1016/j.cccn.2003.09.010 DO - 10.1016/j.cccn.2003.09.010 ID - Wu2004 ER - TY - JOUR AU - Nakamura, T. AU - Fujiwara, N. AU - Sugaya, T. AU - Ueda, Y. AU - Koide, H. PY - 2009 DA - 2009// TI - Effect of red wine on urinary protein, 8-hydroxydeoxyguanosine, and liver-type fatty acid-binding protein excretion in patients with diabetic nephropathy JO - Metabolism VL - 58 UR - https://doi.org/10.1016/j.metabol.2009.03.019 DO - 10.1016/j.metabol.2009.03.019 ID - Nakamura2009 ER - TY - JOUR AU - Loft, S. AU - Vistisen, K. AU - Ewertz, M. AU - Tjonneland, A. AU - Overvad, K. AU - Poulsen, H. E. PY - 1992 DA - 1992// TI - Oxidative DNA damage estimated by 8-hydroxydeoxyguanosine excretion in humans: influence of smoking, gender and body mass index JO - Carcinogenesis VL - 13 UR - https://doi.org/10.1093/carcin/13.12.2241 DO - 10.1093/carcin/13.12.2241 ID - Loft1992 ER - TY - JOUR AU - Dandona, P. AU - Thusu, K. AU - Cook, S. AU - Snyder, B. AU - Makowski, J. AU - Armstrong, D. PY - 1996 DA - 1996// TI - Oxidative damage to DNA in diabetes mellitus JO - Lancet VL - 347 UR - https://doi.org/10.1016/S0140-6736(96)90013-6 DO - 10.1016/S0140-6736(96)90013-6 ID - Dandona1996 ER - TY - JOUR AU - Griendling, K. K. AU - FitzGerald, G. A. PY - 2003 DA - 2003// TI - Oxidative stress and cardiovascular injury: part I: basic mechanisms and in vivo monitoring of ROS JO - Circulation VL - 108 UR - https://doi.org/10.1161/01.CIR.0000093660.86242.BB DO - 10.1161/01.CIR.0000093660.86242.BB ID - Griendling2003 ER - TY - JOUR AU - Wiseman, H. AU - Halliwell, B. PY - 1996 DA - 1996// TI - Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer JO - Biochem J VL - 313 UR - https://doi.org/10.1042/bj3130017 DO - 10.1042/bj3130017 ID - Wiseman1996 ER - TY - JOUR AU - Sakano, N. AU - Takahashi, N. AU - Wang, D. H. AU - Sauriasari, R. AU - Takemoto, K. AU - Kanbara, S. PY - 2009 DA - 2009// TI - Plasma 3-nitrotyrosine, urinary 8-isoprostane and 8-OHdG among healthy Japanese people JO - Free Radic Res VL - 43 UR - https://doi.org/10.1080/10715760802663124 DO - 10.1080/10715760802663124 ID - Sakano2009 ER - TY - JOUR AU - Hasham, S. N. AU - Pillarisetti, S. PY - 2006 DA - 2006// TI - Vascular lipases, inflammation and atherosclerosis JO - Clin Chim Acta VL - 372 UR - https://doi.org/10.1016/j.cca.2006.04.020 DO - 10.1016/j.cca.2006.04.020 ID - Hasham2006 ER - TY - JOUR AU - Chiu, H. K. AU - Qian, K. AU - Ogimoto, K. AU - Morton, G. J. AU - Wisse, B. E. AU - Agrawal, N. PY - 2010 DA - 2010// TI - Mice lacking hepatic lipase are lean and protected against diet-induced obesity and hepatic steatosis JO - Endocrinology VL - 151 UR - https://doi.org/10.1210/en.2009-1100 DO - 10.1210/en.2009-1100 ID - Chiu2010 ER - TY - JOUR AU - Andrés-Blasco, I. AU - Herrero-Cervera, A. AU - Vinué, Á. AU - Martínez-Hervás, S. AU - Piqueras, L. AU - Sanz, M. J. PY - 2015 DA - 2015// TI - Hepatic lipase deficiency produces glucose intolerance, inflammation and hepatic steatosis JO - J Endocrinol VL - 227 UR - https://doi.org/10.1530/JOE-15-0219 DO - 10.1530/JOE-15-0219 ID - Andrés-Blasco2015 ER - TY - JOUR AU - Ridker, P. M. AU - Buring, J. E. AU - Cook, N. R. AU - Rifai, N. PY - 2003 DA - 2003// TI - C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14,719 initially healthy American women JO - Circulation VL - 107 UR - https://doi.org/10.1161/01.CIR.0000055014.62083.05 DO - 10.1161/01.CIR.0000055014.62083.05 ID - Ridker2003 ER - TY - JOUR AU - Hsu, L. A. AU - Ko, Y. L. AU - Wu, S. AU - Teng, M. S. AU - Chou, H. H. AU - Chang, C. J. PY - 2009 DA - 2009// TI - Association of soluble intercellular adhesion molecule-1 with insulin resistance and metabolic syndrome in Taiwanese JO - Metabolism VL - 58 UR - https://doi.org/10.1016/j.metabol.2009.02.021 DO - 10.1016/j.metabol.2009.02.021 ID - Hsu2009 ER - TY - STD TI - Teng MS, Wu S, Er LK, Hsu LA, Chou HH, Ko YL. LIPC variants as genetic determinants of adiposity status, visceral adiposity indicators, and triglyceride-glucose (TyG) index-related parameters mediated by serum triglyceride levels. Diabetol Metab Syndr. 2018;10:79. https://doi.org/10.1186/s13098-018-0383-9. eCollection 2018. ID - ref37 ER - TY - JOUR AU - Teng, M. S. AU - Hsu, L. A. AU - Wu, S. AU - Chou, H. H. AU - Chang, C. J. AU - Sun, Y. Z. PY - 2013 DA - 2013// TI - Mediation analysis reveals a sex-dependent association between ABO gene variants and TG/HDL-C ratio that is suppressed by sE-selectin level JO - Atherosclerosis VL - 228 UR - https://doi.org/10.1016/j.atherosclerosis.2013.03.032 DO - 10.1016/j.atherosclerosis.2013.03.032 ID - Teng2013 ER - TY - JOUR AU - Baron, R. M. AU - Kenny, D. A. PY - 1986 DA - 1986// TI - The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations JO - J Pers Soc Psychol VL - 51 UR - https://doi.org/10.1037/0022-3514.51.6.1173 DO - 10.1037/0022-3514.51.6.1173 ID - Baron1986 ER - TY - JOUR AU - MacKinnon, D. P. PY - 1994 DA - 1994// TI - Analysis of mediating variables in prevention and intervention research JO - NIDA Res Monogr VL - 139 ID - MacKinnon1994 ER - TY - JOUR AU - Sobel, M. E. PY - 1987 DA - 1987// TI - Direct and indirect effects in linear structural equation models JO - Sociol Methods Res VL - 16 UR - https://doi.org/10.1177/0049124187016001006 DO - 10.1177/0049124187016001006 ID - Sobel1987 ER - TY - JOUR AU - MacKinnon, D. P. AU - Krull, J. L. AU - Lockwood, C. M. PY - 2000 DA - 2000// TI - Equivalence of the mediation, confounding and suppression effect JO - Prev Sci VL - 1 UR - https://doi.org/10.1023/A:1026595011371 DO - 10.1023/A:1026595011371 ID - MacKinnon2000 ER - TY - JOUR AU - Sobel, M. E. PY - 1982 DA - 1982// TI - Asymptotic confidence intervals for indirect effects in structural equation models JO - Sociol Methodol VL - 13 UR - https://doi.org/10.2307/270723 DO - 10.2307/270723 ID - Sobel1982 ER - TY - JOUR AU - Kraja, A. T. AU - Vaidya, D. AU - Pankow, J. S. AU - Goodarzi, M. O. AU - Assimes, T. L. AU - Kullo, I. J. PY - 2011 DA - 2011// TI - A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium JO - Diabetes VL - 60 UR - https://doi.org/10.2337/db10-1011 DO - 10.2337/db10-1011 ID - Kraja2011 ER - TY - JOUR AU - Zhou, L. AU - He, M. AU - Mo, Z. AU - Wu, C. AU - Yang, H. AU - Yu, D. PY - 2013 DA - 2013// TI - A genome wide association study identifies common variants associated with lipid levels in the Chinese population JO - PLoS One VL - 8 UR - https://doi.org/10.1371/journal.pone.0082420 DO - 10.1371/journal.pone.0082420 ID - Zhou2013 ER - TY - JOUR AU - Folkersen, L. AU - van't Hooft, F. AU - Chernogubova, E. AU - Agardh, H. E. AU - Hansson, G. K. AU - Hedin, U. PY - 2010 DA - 2010// TI - Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease JO - Circ Cardiovasc Genet VL - 3 UR - https://doi.org/10.1161/CIRCGENETICS.110.948935 DO - 10.1161/CIRCGENETICS.110.948935 ID - Folkersen2010 ER - TY - JOUR AU - Ma, L. AU - Ballantyne, C. AU - Brautbar, A. AU - Keinan, A. PY - 2014 DA - 2014// TI - Analysis of multiple association studies provides evidence of an expre ssion QTL hub in gene-gene interaction network affecting HDL cholesterol levels JO - PLoS One VL - 9 UR - https://doi.org/10.1371/journal.pone.0092469 DO - 10.1371/journal.pone.0092469 ID - Ma2014 ER - TY - JOUR AU - Meng, Q. AU - Huang, L. AU - Sun, Y. AU - Bai, Y. AU - Wang, B. AU - Yu, W. PY - 2015 DA - 2015// TI - Effect of high-density lipoprotein metabolic pathway gene variations and risk factors on neovascular age-related macular degeneration and polypoidal choroidal vasculopathy in China JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0143924 DO - 10.1371/journal.pone.0143924 ID - Meng2015 ER - TY - JOUR AU - Simmons, C. R. AU - Zou, F. AU - Younkin, S. G. AU - Estus, S. PY - 2011 DA - 2011// TI - Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk JO - Mol Neurodegener VL - 6 UR - https://doi.org/10.1186/1750-1326-6-62 DO - 10.1186/1750-1326-6-62 ID - Simmons2011 ER - TY - JOUR AU - Evans, M. D. AU - Dizdaroglu, M. AU - Cooke, M. S. PY - 2004 DA - 2004// TI - Oxidative DNA damage and disease: induction, repair and significance JO - Mutat Res VL - 567 UR - https://doi.org/10.1016/j.mrrev.2003.11.001 DO - 10.1016/j.mrrev.2003.11.001 ID - Evans2004 ER - TY - JOUR AU - Chen, W. AU - Stambolian, D. AU - Edwards, A. O. AU - Branham, K. E. AU - Othman, M. AU - Jakobsdottir, J. PY - 2010 DA - 2010// TI - Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.0912702107 DO - 10.1073/pnas.0912702107 ID - Chen2010 ER - TY - JOUR AU - Neale, B. M. AU - Fagerness, J. AU - Reynolds, R. AU - Sobrin, L. AU - Parker, M. AU - Raychaudhuri, S. PY - 2010 DA - 2010// TI - Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC) JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.0912019107 DO - 10.1073/pnas.0912019107 ID - Neale2010 ER - TY - JOUR AU - Seddon, J. M. AU - Reynolds, R. AU - Rosner, B. PY - 2010 DA - 2010// TI - Associations of smoking, body mass index, dietary lutein, and the LIPC gene variant rs10468017 with advanced age-related macular degeneration JO - Mol Vis VL - 16 ID - Seddon2010 ER - TY - JOUR AU - Jarrett, S. G. AU - Boulton, M. E. PY - 2012 DA - 2012// TI - Consequences of oxidative stress in age-related macular degeneration JO - Mol Asp Med VL - 33 UR - https://doi.org/10.1016/j.mam.2012.03.009 DO - 10.1016/j.mam.2012.03.009 ID - Jarrett2012 ER - TY - JOUR AU - Ahmad, T. AU - Chasman, D. I. AU - Buring, J. E. AU - Lee, I. M. AU - Ridker, P. M. AU - Everett, B. M. PY - 2011 DA - 2011// TI - Physical activity modifies the effect of LPL, LIPC, and CETP polymorphisms on HDL-C levels and the risk of myocardial infarction in women of European ancestry JO - Circ Cardiovasc Genet VL - 4 UR - https://doi.org/10.1161/CIRCGENETICS.110.957290 DO - 10.1161/CIRCGENETICS.110.957290 ID - Ahmad2011 ER - TY - JOUR AU - Grarup, N. AU - Andreasen, C. H. AU - Andersen, M. K. AU - Albrechtsen, A. AU - Sandbaek, A. AU - Lauritzen, T. PY - 2008 DA - 2008// TI - The -250G>a promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects JO - J Clin Endocrinol Metab VL - 93 UR - https://doi.org/10.1210/jc.2007-2815 DO - 10.1210/jc.2007-2815 ID - Grarup2008 ER - TY - JOUR AU - Lopez-Rios, L. AU - Novoa, F. J. AU - Chirino, R. AU - Varillas, F. AU - Boronat-Cortes, M. AU - Wagner, A. M. PY - 2011 DA - 2011// TI - Interaction between cholesteryl ester transfer protein and hepatic lipase encoding genes and the risk of type 2 diabetes: results from the Telde study JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0027208 DO - 10.1371/journal.pone.0027208 ID - Lopez-Rios2011 ER - TY - JOUR AU - St-Pierre, J. AU - Miller-Felix, I. AU - Paradis, M. E. AU - Bergeron, J. AU - Lamarche, B. AU - Despres, J. P. PY - 2003 DA - 2003// TI - Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men JO - Mol Genet Metab VL - 78 UR - https://doi.org/10.1016/S1096-7192(02)00223-8 DO - 10.1016/S1096-7192(02)00223-8 ID - St-Pierre2003 ER - TY - JOUR AU - Yin, R. X. AU - Wu, D. F. AU - Miao, L. AU - Aung, L. H. AU - Cao, X. L. AU - Yan, T. T. PY - 2012 DA - 2012// TI - Several genetic polymorphisms interact with overweight/obesity to influence serum lipid levels JO - Cardiovasc Diabetol VL - 11 UR - https://doi.org/10.1186/1475-2840-11-123 DO - 10.1186/1475-2840-11-123 ID - Yin2012 ER - TY - JOUR AU - Zhang, C. AU - Lopez-Ridaura, R. AU - Rimm, E. B. AU - Rifai, N. AU - Hunter, D. J. AU - Hu, F. B. PY - 2005 DA - 2005// TI - Interactions between the -514C->T polymorphism of the hepatic lipase gene and lifestyle factors in relation to HDL concentrations among US diabetic men JO - Am J Clin Nutr VL - 81 UR - https://doi.org/10.1093/ajcn/81.6.1429 DO - 10.1093/ajcn/81.6.1429 ID - Zhang2005 ER - TY - JOUR AU - Ko, Y. L. AU - Hsu, L. A. AU - Wu, S. AU - Teng, M. S. AU - Chou, H. H. PY - 2016 DA - 2016// TI - CRP and SAA1 haplotypes are associated with both C-reactive protein and serum amyloid a levels: role of suppression effects JO - Mediat Inflamm VL - 2016 ID - Ko2016 ER - TY - JOUR AU - Teng, M. S. AU - Hsu, L. A. AU - Wu, S. AU - Sun, Y. C. AU - Juan, S. H. AU - Ko, Y. L. PY - 2015 DA - 2015// TI - Association of CDH13 genotypes/haplotypes with circulating adiponectin levels, metabolic syndrome, and related metabolic phenotypes: the role of the suppression effect JO - PLoS One VL - 10 UR - https://doi.org/10.1371/journal.pone.0122664 DO - 10.1371/journal.pone.0122664 ID - Teng2015 ER - TY - JOUR AU - Solovieff, N. AU - Cotsapas, C. AU - Lee, P. H. AU - Purcell, S. M. AU - Smoller, J. W. PY - 2013 DA - 2013// TI - Pleiotropy in complex traits: challenges and strategies JO - Nat Rev Genet VL - 14 UR - https://doi.org/10.1038/nrg3461 DO - 10.1038/nrg3461 ID - Solovieff2013 ER - TY - JOUR AU - Sivakumaran, S. AU - Agakov, F. AU - Theodoratou, E. AU - Prendergast, J. G. AU - Zgaga, L. AU - Manolio, T. PY - 2011 DA - 2011// TI - Abundant pleiotropy in human complex diseases and traits JO - Am J Hum Genet VL - 89 UR - https://doi.org/10.1016/j.ajhg.2011.10.004 DO - 10.1016/j.ajhg.2011.10.004 ID - Sivakumaran2011 ER - TY - JOUR AU - Teslovich, T. M. AU - Fuchsberger, C. AU - Ramensky, V. AU - Yajnik, P. AU - Koboldt, D. C. PY - 2014 DA - 2014// TI - Re-sequencing expands our understanding of the phenotypic impact of variants at GWAS loci JO - PLoS Genet VL - 10 UR - https://doi.org/10.1371/journal.pgen.1004147 DO - 10.1371/journal.pgen.1004147 ID - Teslovich2014 ER - TY - JOUR AU - Demirkan, A. AU - Duijn, C. M. AU - Ugocsai, P. AU - Isaacs, A. AU - Pramstaller, P. P. AU - Liebisch, G. PY - 2012 DA - 2012// TI - Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations JO - PLoS Genet VL - 8 UR - https://doi.org/10.1371/journal.pgen.1002490 DO - 10.1371/journal.pgen.1002490 ID - Demirkan2012 ER - TY - JOUR AU - Cipriani, V. AU - Leung, H. T. AU - Plagnol, V. AU - Bunce, C. AU - Khan, J. C. AU - Shahid, H. PY - 2012 DA - 2012// TI - Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3 JO - Hum Mol Genet VL - 21 UR - https://doi.org/10.1093/hmg/dds225 DO - 10.1093/hmg/dds225 ID - Cipriani2012 ER -