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Fig. 1 | Lipids in Health and Disease

Fig. 1

From: Inhibition of FASN suppresses the malignant biological behavior of non-small cell lung cancer cells via deregulating glucose metabolism and AKT/ERK pathway

Fig. 1

Target genes’ relative expressions detected by RT-qPCR after LV–siFASN transfection. The relative expressions of target genes in each group are shown relative to those of the blank group. FASN mRNA expressions were significantly decreased in the experimental group of A549 cells (P < 0.05; a) and NCI-H1299 cells (P < 0.05; b), suggesting that LV–FASN RNAi successfully suppressed the expression of FASN. Additionally, AZGP1 expression was lower under FASN deficiency in A549 cells (P < 0.05; a) and NCI-H1299 cells (P < 0.05; b). The differences between the Akt-mRNA and ERK-mRNA expressions of each group of A549 cells (a) and NCI-H1299 cells (b) were not statistically significant. * compared to the control group (P < 0.05). # compared to the blank group (P < 0.05)

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Lipids in Health and Disease

ISSN: 1476-511X