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Table 2 Associaiton between chromosome 12p13 SNPs and risk of IS

From: A functional variant rs12904 in the miR-200c binding site was associated with a decreased risk of ischemic stroke

Genotypes

Controls, n = 331 (%)

IS, n = 328 (%)

Adjusted OR (95% CI) a

Adjusted P value a

rs12425791

 GG

184 (55.6)

172 (52.4)

1.00

 

 AG/AA

147 (44.4)

156 (47.6)

1.02 (0.73–1.42)

0.90

 G

486 (73.4)

476 (72.6)

1.00

 

 A

176 (26.6)

180 (27.4)

1.00 (0.76–1.29)

0.97

rs11833579

 GG

161 (48.6)

171 (52.1)

1.00

 

 AG/AA

170 (51.4)

157 (47.9)

0.89 (0.64–1.24)

0.49

 G

452 (68.3)

467 (71.2)

1.00

 

 A

210 (31.7)

189 (28.8)

0.89 (0.69–1.14)

0.35

rs12904

 AA

237 (71.6)

262 (79.9)

1.00

 

 AG/GG

94 (28.4)

66 (20.1)

0.64 (0.44–0.95)

0.03

 A

556 (84.0)

584 (89.0)

1.00

 

 G

106 (16.0)

72 (11.0)

0.65 (0.46–0.93)

0.02

  1. SNP single nucletide polymorphism, IS ischemic stroke, OR odds ratio, CI confidence interval. aAdjusted by age, gender, hypertension, type 2 diabetes, and smoking