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Table 4 Combined effects of chromosome 12p13 SNPs on the risk of IS

From: A functional variant rs12904 in the miR-200c binding site was associated with a decreased risk of ischemic stroke

Combined genotypes

Controls (%)

IS (%)

OR (95% CI)

P value

rs12425791- rs12904

 rs12425791GG + rs12904AA

136 (41.1)

141 (43.0)

1.00

 

 rs12425791GG + rs12904AG/GG

48 (14.5)

31 (9.5)

0.62 (0.37–1.04)

0.07

 rs12425791AG/AA + rs12904AA

101 (30.5)

121 (36.9)

1.16 (0.81–1.65)

0.42

 rs12425791AG/AA + rs12904AG/GG

46 (13.9)

35 (10.7)

0.73 (0.45–1.21)

0.22

rs11833579- rs12904

 rs11833579GG + rs12904AA

117 (35.3)

138 (42.1)

1.00

 

 rs11833579GG + rs12904AG/GG

44 (6.7)

33 (10.1)

0.64 (0.38–1.06)

0.08

 rs11833579AG/AA + rs12904AA

120 (36.3)

124 (37.8)

0.88 (0.62–1.25)

0.46

 rs11833579AG/AA + rs12904AG/GG

50 (7.6)

33 (10.1)

0.56 (0.34–0.93)

0.02

  1. SNP single nucletide polymorphism, IS ischemic stroke, OR odds ratio, CI confidence interval