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Table 5 Screening of analgesic activity of selected formulations using cold plate test in rats

From: Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model

S.No.

Treatment

Reaction time (sec.)

15 min

30 min

45 min

60 min

I

Brugel Gel

16.9 ± 2.02

17.7 ± 2.4

19 ± 2.21

19.8 ± 2.41

II

Etho 5 (10 mg/kg)

15.33 ± 0.51ns

16.8 ± 0.63ns

19.2 ± 0.63ns

21 ± 0.63ns

III

Etho 5 (20 mg/kg)

15.66 ± 0.81ns

17.48 ± 0.5 ns

21.66 ± 0.51**

25.16 ± 0.40***

  1. ns Not significant
  2. **Significant
  3. ***Highly significant