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Table 6 Screening of anti-inflammatory activity of selected formulation in carrageenan induced paw edema in rats

From: Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model

S.No. Treatment Swelling index (cm)
15 min 30 min 45 min 60 min 75 min 90 min
I Brugel Gel 2.81 ± 0.04 2.76 ± 0.05 2.68 ± 0.04 2.63 ± 0.05 2.59 ± 0.06 2.55 ± 0.05
II Etho5 (10 mg/kg) 2.83 ± 0.05ns 2.7 ± 0.06ns 2.66 ± 0.05ns 2.53 ± 0.05*** 2.45 ± 0.05*** 2.41 ± 0.04***
III Etho5 (20 mg/kg) 2.82 ± 0.06ns 2.67 ± 0.05*** 2.62 ± 0.06ns 2.55 ± 0.05ns 2.45 ± 0.05*** 2.35 ± 0.05***
  1. ns Not significant
  2. **Significant
  3. ***Highly significant