Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia

Table 2 Odds ratio of hyperuricemia among fasting plasma triglyceride (mmol/L) in men and women^a

	Men, fasting plasma triglyceride (mmol/L)						Women, fasting plasma triglyceride (mmol/L)
	< 1.21	1.21 ~	1.7 ~	2.83 ~	> 5.6	P for trend^b	< 1.21	1.21 ~	1.7 ~	2.83 ~	> 5.6	P for trend^b
No. of participants	4293	3040	3335	1546	343		6023	2661	2353	747	97
Hyperuricemia^c
Cases	225	249	387	300	91		146	154	241	133	14
Rate (%)	5.2	8.2	11.6	19.4	26.5		2.4	5.8	10.2	17.8	14.4
Model 1, OR (95% CI)	1.00	1.61 (1.34–1.94)	2.37 (2.00–2.82)	4.35 (3.62–5.23)	6.53 (4.96–8.59)	0.000	1.00	2.47 (1.96–3.12)	4.59 (3.72–5.68)	8.72 (6.80–11.19)	6.79 (3.77–12.24)	0.000
Model 2, OR (95% CI)	1.00	1.62 (1.35–1.96)	2.37 (2.00–2.81)	4.26 (3.54–5.12)	6.26 (4.76–8.25)	0.000	1.00	2.35 (1.86–2.97)	4.28 (3.44–5.33)	8.16 (6.33–10.53)	6.43 (3.56–11.61)	0.000
Model 3, OR (95% CI)	1.00	1.46 (1.21–1.77)	1.99 (1.65–2.39)	3.10 (2.51–3.82)	4.27 (3.13–5.83)	0.000	1.00	1.95 (1.53–2.50)	3.20 (2.51–4.08)	5.42 (4.03–7.28)	4.01 (2.13–7.55)	0.000

^aLogistic regression. Model 1, univariate; Model 2, adjusted with age; Model 3, adjusted with age, alanine aminotransferase (U/L), γ-glutamyl transpeptidase (U/L), serum creatinine (mmol/L), blood urea nitrogen (μmol/L), total cholesterol (mmol/L), plasma glucose (mmol/l), and high density lipoprotein cholesterol (mmol/L). OR Odds ratio, CI Confidence interval
^bContrasts of marginal linear predictions after logistic regression with Stata13
^cHyperuricemia:(men > 440 μmol/L or women > 360 μmol/L

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