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Table 5 Odds ratio of hyperuricemia among triglyceride-glucose index and age in men and womena

From: Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia

 

Men, triglyceride-glucose index (TyG)

Women, triglyceride-glucose index (TyG)

No. of participants

Case

Rate (%)

0 ~

1st quatile ~

2nd quatile ~

3rd quatile ~

P for trendb

No. of participants

Case

Rate (%)

0 ~

1st quatile ~

2nd quatile ~

3rd quatile ~

P for trendb

No. of participants

12,557

1252

10.0

2169

3034

3410

3944

 

11,881

688

5.8

3924

3057

2701

2199

 

Hyperuricemiac

 < 20 yrs

43

10

23.3

1.00

4.98 (0.37–66.42)

73.31 (1.18–4529.68)

7.78 (0.20–297.59)

0.135

22

3

13.6

1.00

(−)

(−)

(−)

(−)

 20~ yrs

1325

175

13.2

1.00

1.19 (0.70–2.77)

1.29 (0.76–2.18)

2.44 (1.41–4.24)

0.002

1880

116

6.2

1.00

2.77 (1.50–5.97)

2.49 (1.23–5.23)

5.72 (2.82–11.61)

<  0.001

 30~ yrs

2348

304

12.9

1.00

1.30 (0.77–2.21)

1.83 (1.11–3.32)

2.27 (1.36–3.78)

<  0.001

2485

107

4.3

1.00

1.89 (0.96–3.69)

4.15 (2.18–7.89)

5.95 (2.92–12.11)

<  0.000

 40~ yrs

3133

288

9.2

1.00

0.98 (0.51–1.89)

2.03 (1.13–3.65)

3.77 (2.12–6.72)

<  0.001

2652

74

2.8

1.00

3.61 (1.29–13.86)

9.42 (3.42–25.97)

11.42 (3.87–33.73)

<  0.001

 50~ yrs

2735

241

8.8

1.00

1.54 (0.81–2.93)

1.92 (1.04–3.54)

3.31 (1.80–6.75)

<  0.001

2492

159

6.4

1.00

0.91 (0.46–1.79)

1.64 (0.87–3.57)

2.86 (1.51–5.42)

0.002

 60~ yrs

1848

123

6.7

1.00

3.17 (1.06–9.46)

4.90 (1.67–14.37)

6.46 (2.19–19.53)

<  0.001

1509

123

8.2

1.00

2.27 (0.62–8.31)

3.98 (1.18–13.47)

10.67 (3.17–35.98)

<  0.001

 70~ yrs

848

81

9.6

1.00

1.48 (0.62–3.54)

1.35 (0.54–3.36)

1.34 (0.53–3.41)

0.600

679

78

11.5

1.00

0.97 (0.30–3.14)

1.60 (0.53–4.78)

2.25 (0.74–6.83)

0.198

 80~ yrs

277

30

10.8

1.00

1.39 (0.29–6.72)

6.16 (1.51–25.72)

3.68 (0.72–18.71)

0.035

162

28

17.3

(−)

1.00

3.08 (0.67–14.27)

5.24 (1.10–24.87)

0.321

  1. aLogistic regression model adjusted with alanine aminotransferase (U/L), γ-glutamyl transpeptidase (U/L), serum creatinine (mmol/L), blood urea nitrogen (μmol/L), total cholesterol (mmol/L), and high density lipoprotein cholesterol (mmol/L)
  2. bContrasts of marginal linear predictions from 3.9~ though > 7.0 groups after logistic regression with Stata13
  3. cHyperuricemia: men > 440 μmol/L or women > 360 μmol/L