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Table 5 Odds ratio of hyperuricemia among triglyceride-glucose index and age in men and womena

From: Age-related and gender-stratified differences in the association between high triglyceride and risk of hyperuricemia

  Men, triglyceride-glucose index (TyG) Women, triglyceride-glucose index (TyG)
No. of participants Case Rate (%) 0 ~ 1st quatile ~ 2nd quatile ~ 3rd quatile ~ P for trendb No. of participants Case Rate (%) 0 ~ 1st quatile ~ 2nd quatile ~ 3rd quatile ~ P for trendb
No. of participants 12,557 1252 10.0 2169 3034 3410 3944   11,881 688 5.8 3924 3057 2701 2199  
Hyperuricemiac
 < 20 yrs 43 10 23.3 1.00 4.98 (0.37–66.42) 73.31 (1.18–4529.68) 7.78 (0.20–297.59) 0.135 22 3 13.6 1.00 (−) (−) (−) (−)
 20~ yrs 1325 175 13.2 1.00 1.19 (0.70–2.77) 1.29 (0.76–2.18) 2.44 (1.41–4.24) 0.002 1880 116 6.2 1.00 2.77 (1.50–5.97) 2.49 (1.23–5.23) 5.72 (2.82–11.61) <  0.001
 30~ yrs 2348 304 12.9 1.00 1.30 (0.77–2.21) 1.83 (1.11–3.32) 2.27 (1.36–3.78) <  0.001 2485 107 4.3 1.00 1.89 (0.96–3.69) 4.15 (2.18–7.89) 5.95 (2.92–12.11) <  0.000
 40~ yrs 3133 288 9.2 1.00 0.98 (0.51–1.89) 2.03 (1.13–3.65) 3.77 (2.12–6.72) <  0.001 2652 74 2.8 1.00 3.61 (1.29–13.86) 9.42 (3.42–25.97) 11.42 (3.87–33.73) <  0.001
 50~ yrs 2735 241 8.8 1.00 1.54 (0.81–2.93) 1.92 (1.04–3.54) 3.31 (1.80–6.75) <  0.001 2492 159 6.4 1.00 0.91 (0.46–1.79) 1.64 (0.87–3.57) 2.86 (1.51–5.42) 0.002
 60~ yrs 1848 123 6.7 1.00 3.17 (1.06–9.46) 4.90 (1.67–14.37) 6.46 (2.19–19.53) <  0.001 1509 123 8.2 1.00 2.27 (0.62–8.31) 3.98 (1.18–13.47) 10.67 (3.17–35.98) <  0.001
 70~ yrs 848 81 9.6 1.00 1.48 (0.62–3.54) 1.35 (0.54–3.36) 1.34 (0.53–3.41) 0.600 679 78 11.5 1.00 0.97 (0.30–3.14) 1.60 (0.53–4.78) 2.25 (0.74–6.83) 0.198
 80~ yrs 277 30 10.8 1.00 1.39 (0.29–6.72) 6.16 (1.51–25.72) 3.68 (0.72–18.71) 0.035 162 28 17.3 (−) 1.00 3.08 (0.67–14.27) 5.24 (1.10–24.87) 0.321
  1. aLogistic regression model adjusted with alanine aminotransferase (U/L), γ-glutamyl transpeptidase (U/L), serum creatinine (mmol/L), blood urea nitrogen (μmol/L), total cholesterol (mmol/L), and high density lipoprotein cholesterol (mmol/L)
  2. bContrasts of marginal linear predictions from 3.9~ though > 7.0 groups after logistic regression with Stata13
  3. cHyperuricemia: men > 440 μmol/L or women > 360 μmol/L